-Caveat Lector-

----- Original Message -----
From: "F.M.Sielaff" <[EMAIL PROTECTED]>
To: "Freedom Forum" <[EMAIL PROTECTED]>; "Friendly Patriotic
Exchange" <[EMAIL PROTECTED]>
Sent: Wednesday, November 29, 2000 12:16 AM
Subject: [FPE] California Researchers Defend Using Humans


> Courtesy of the AP at http://ap.tbo.com/ap/breaking/MGAIM7QB4GC.html for
> our ongoing education regarding "beneficial" scientific research.
>
> Nov 28, 2000 - 08:07 PM
> California Researchers Defend Using Humans in Study of Toxin
>
> By Tom Verdin
> Associated Press Writer
>
> LOMA LINDA, Calif. (AP) - Doctors doing a study of a toxic water
> pollutant defended feeding it to human participants, saying the
> potential medical benefit outweighed the risk.
>
> The Loma Linda University Medical Center researchers held a news
> conference Tuesday to respond to media reports raising concerns about
> people being given doses of perchlorate, a chemical used in rocket fuel
> that has contaminated ground water in parts of Southern California.
>
> The hospital's institutional review board, which oversees clinical
> trials, concluded that participants would face minimal risk. Researchers
> said the perchlorate doses being given in the study are about 100 times
> lower than those given to people who are prescribed perchlorate for
> thyroid illnesses.
>
> Dr. Anthony Firek, the study's principal investigator, said the dosages
> are also lower than those given in a study published earlier this year
> by Harvard University. Nine men received 10 milligrams of perchlorate
> daily in that study.
>
> Loma Linda researchers are giving participants doses ranging from a
> half-milligram to three milligrams. Half of the participants get
> placebos.
>
> But the daily doses in the Loma Linda study are still up to 83 times
> higher than drinking-water limits for perchlorate recommended by
> California's Department of Health Services.
>
> Dr. William Saukel, chairman of Loma Linda's review board, said the
> study likely will produce information beneficial to the population as a
> whole.
>
> So far, just eight people have enrolled in the study, which began in
> early October. Researchers hope to eventually enroll 100 people who each
> will be paid $1,000 for seven months of participation.
>
> Participants are informed of the risks of the research, which include
> bone marrow suppression, lessening of white and red blood cell counts
> and thyroid problems.
>
> Lockheed Martin - which faces hundreds of lawsuits accusing it of
> creating perchlorate pollution and threatening the health of San
> Bernardino and Riverside counties' residents - is paying for the study.
> The aerospace company's officials have said the study will help
> determine the health risk of perchlorate.
>
> Barry Taylor, Loma Linda's vice president for research affairs, said
> university officials discussed the company's possible motivations. "But
> on the other hand," he said, "people on the committee recognized that
> they could see medical use coming out of this."
>
> The idea for the study came from medical researchers, not Lockheed,
> researchers said.
>
> Firek said the study is being conducted to determine how best to
> diagnose and treat any illnesses caused by perchlorate in drinking
> water.
>
> Perchlorate has been used as a rocket-fuel oxidizer since the 1940s, and
> is thought to have contaminated water supplies in parts of Riverside and
> San Bernardino counties, as well as the San Gabriel Valley east of Los
> Angeles.
>
> In large doses, it can slow down the thyroid, which produces the hormone
> that controls infants' brain development and growth in older children.
> In adults, the thyroid regulates such things as temperature and blood
> cholesterol. Some people with thyroid illnesses are prescribed
> perchlorate to help treat their conditions.
>
> Firek indicated that doctors treating such patients are seeing some
> problems they think could be related to perchlorate. A clinical trial is
> the only way to determine whether that is the case, he said.
>
> ---
>
> On the Net:
> Perchlorate information:
> http://www.epa.gov/safewater/ccl/perchlor/perchlo.html
> Loma Linda Medical Center: http://www.llu.edu/llumc/
>
>
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>

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