-Caveat Lector-

from - http://dailynews.yahoo.com/h/ap/20020108/us/tampa_crash_8.html

Tuesday January 8 7:30 PM ET

Fla. Pilot Took Controversial Drug

By VICKIE CHACHERE, Associated Press Writer

TAMPA, Fla. (AP) - A 15-year-old student pilot who killed himself by
crashing an airplane into a skyscraper was prescribed an acne medication
whose links to suicide and depression have been the subject of federal
inquiries, law enforcement officials said Tuesday.

A prescription for Accutane, used to treat severe acne, was found at the
home of Charles J. Bishop, Pinellas County Sheriff's Maj. Sam Lynn said.

``We are aware that he had a prescription,'' Tampa police spokeswoman Katie
Hughes said. ``We don't know if he was taking it, how long ... We don't know
those details.''

Calls to Bishop's family were not returned Tuesday.

The Food and Drug Administration (news - web sites) says 147 people taking
Accutane, which affects the body's central nervous system, either committed
suicide or were hospitalized for suicide attempts from 1982 to May 2000.

There has yet to be any conclusive evidence, however, that the drug causes
depression or suicide, and the manufacturer maintains it is safe.

Toxicology tests that will determine if any drugs were in Bishop's system
will be completed in about two weeks, said Lee Miller, an associate medical
examiner with the Hillsborough County Medical Examiner's Office.

Bishop, a freshman at East Lake High School, stole an airplane from a flight
school at the St. Petersburg-Clearwater International Airport on Saturday
and crashed it into the 28th floor of the Bank of America Plaza in downtown
Tampa. A note expressing sympathy for Osama bin Laden (news - web sites) and
support of the Sept. 11 terrorist attacks was found in his pocket.

Police describe Bishop as a troubled loner. But the youth's family, teachers
and flight instructors said he never showed any signs of depression and that
his actions Saturday were out of character.

His family and teachers have described him as an intelligent, friendly young
man who was not isolated from others.

Bishop's best friend, 15-year-old Emerson Favreau, said Tuesday that Bishop
didn't seem depressed, and in fact, seemed happy.

``People who commit suicide don't usually talk about what they want to do in
the future,'' Favreau said. ``He talked all the time about being an airline
pilot. He wanted to fly 747s.''

But two days before he crashed the plane into the building, Favreau said
Bishop told him he was going to be on the news. Favreau said he didn't think
anything of it because his friend had made the claim before.

``This time when I heard a Cessna hit the building, what he said popped into
my head,'' Favreau said. ``I knew it had to be him.''

Hughes said Tuesday that the FBI (news - web sites) has found no evidence
worth pursuing on the computer hard drives taken from the homes of Bishop
and his grandmother. The FBI has subpoenaed Bishop's e-mail in the search
for more clues.

Police have said Bishop had no history of psychological problems or illegal
drug use.

Accutane's link to suicide has been the subject of a congressional
investigation, spearheaded by Rep. Bart Stupak (news), D-Michigan, whose
17-year-old son committed suicide while taking the drug. More hearings are
scheduled this spring.

Depression has been listed as a possible side effect on Accutane's label
since 1986, and the FDA in 1998 strengthened the warning to say suicide,
too, was possible.

Since last year, doctors prescribing Accutane have been asked to have
patients read and sign an informed consent form warning that some people
have developed mental problems while taking the drug.

The makers of the drug, Hoffman-La Roche, have agreed to conduct a study
looking at the link between the drug's use and depression, which will begin
later this year, company spokeswoman Carolyn Glynn said.

The company denies the drug can cause people to become depressed or
suicidal, and said the number of suicides by Accutane users is lower than
the general population.

Accutane has been marketed as an acne drug since 1982 and an estimated 12
million patients have used it. The first reports of its connection to
suicide and depression came in 1985.

Accutane also has been linked to birth defects and carries strong warnings
for women who use it.

Stupak, who has reviewed more than 50 suicides in his investigation of the
drug, said there was no explanation for many of the teen-agers involved
taking their own lives. In some instances in which suicide notes were left
behind, the notes made no sense to survivors, he said.

No one interviewed about Bishop could remember him expressing support for
the Sept. 11 attacks before the plane crash.

``Charles and his family have always fully supported our United States' war
on terrorism and Osama Bin Laden,'' his family said in a statement released
earlier this week.

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