On 5 Apr 2002, Michael Roberts wrote:

> Repeat until they stop their dumb behavior. That should put an end to
> most conflicts I believe.  As for shooting holes in people, isn't that
> what we did in the 20th centrury ?
> 
> Has anyone seen any research on stuff like this ?

You don't even need to open a book on pharmacology to realize why this is
a dumb idea. To have any effect a molecule must enter your body. Because
you use passive vehicles to deliver (unless you can get your target
audience to self-administer in a controlled manner), some people will get
a lot more exposure than others due to statistical fluctuations. Depending
on their age, physique, and natural susceptibility, their reactions will
vary widely even to the same dosage/kg. Since typically you don't drench
the landscape with tons of agent per m^2, the molecules used are potent,
meaning have noticeable impacts even in very small quantities. Their
therapeutic bandwidth (starting from where you get an effect, and when
you're approaching LD50 country, a mg/kg body weight dosage at which 50%
of people die) is narrow.

Taken together, this means that you're walking a *very* narrow line 
between no effect at all, and a lot of dead bodies littering the 
landscape. Both are probably not what you wanted.



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