https://www.technologyreview.com/s/614259/an-important-quantum-algorithm-may-actually-be-a-property-of-nature/

An important quantum algorithm may actually be a property of nature

Evidence that quantum searches are an ordinary feature of electron behavior may 
explain the genetic code, one of the greatest puzzles in biology.

by [Emerging Technology from the 
arXiv](https://www.technologyreview.com/profile/emerging-technology-from-the-arxiv/)
Sep 12, 2019

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Back in 1996, a quantum physicist at Bell Labs in New Jersey published a new 
recipe for searching through a database of N entries. Computer scientists have 
long known that this process takes around N steps because in the worst case, 
the last item on the list could be the one of interest.

However, this physicist, Lov Grover, showed how the strange rules of quantum 
mechanics allowed the search to be done in a number of steps equal to the 
square root of N.

That was a big deal. Searching databases is a foundational task in computer 
science, used for everything from finding telephone numbers to breaking 
cryptographic codes. So any speed-up is a significant advance.

Quantum mechanics provided an additional twist. At the time, Grover’s recipe 
was only the second quantum algorithm that had been proved faster than its 
classical counterpart. (The first was Peter Shor’s algorithm for factoring 
numbers, which he discovered in 1994.) Grover’s work was an important factor in 
preparing the way for the quantum computing revolution that is still ongoing 
today.

But despite the interest, implementing Grover’s algorithm has taken time 
because of the significant technical challenges involved. The first quantum 
computer capable of implementing it appeared in 1998, but the first scalable 
version didn’t appear until 2017, and even then it worked with only three 
qubits. So new ways to implement the algorithm are desperately needed.

Today Stéphane Guillet and colleagues at the University of Toulon in France say 
this may be easier than anybody expected. They say they have evidence that 
Grover’s search algorithm is a naturally occurring phenomenon. “We provide the 
first evidence that under certain conditions, electrons may naturally behave 
like a Grover search, looking for defects in a material,” they say.

That has obvious implications for quantum computing, but its real import may be 
much more profound. For some time, theorists have debated whether quantum 
search could explain one of the greatest mysteries about the origin of life. 
The idea that Grover searches occur in nature could finally solve the conundrum.

First some background. Because it is so fundamental, Grover’s search algorithm 
can be reformulated in a variety of ways. One of these is as a quantum walk 
across a surface—the way a quantum particle would move randomly from one point 
to another.

Clearly, this process is a kind of search of two-dimensional space. But because 
a quantum particle can explore many paths at the same time, it is much faster 
than a classical search.

The nature of the surface has an important influence on the search. For 
example, one type of surface consists of a square grid where the quantum 
particle has four possible moves at each vertex.

But there are many other possible grids; a triangular one, for example, where 
the quantum particle has three choices at each vertex. “The triangular grid is 
of particular interest because of its resemblance to several naturally 
occurring crystal-like materials,” say Guillet and co.

The team focused on simulating the way a Grover search works for electrons 
exploring triangular and square grids, but they also included other physically 
realistic effects, such as defects in the grid in the form of holes, and 
quantum properties such as interference effects.

[Quantum walk]

The results are eye-opening. The question they ask is how quickly an electron 
can find the hole in a grid. And the team’s big breakthrough is to show that 
these simulations reproduce the way real electrons behave in real materials.

In other words, this is evidence that free electrons naturally implement the 
Grover search algorithm when moving across the surface of certain crystals.

That has immediate implications for quantum computing. “[This work] may be the 
path to a serious technological leap, whereby experimentalist would bypass the 
need for a full-fledged scalable and error-correcting Quantum Computer, and 
take the shortcut of looking for ‘natural occurrences’ of the Grover search 
instead,” say the team.

The work also has implications for our thinking about the genetic code and the 
origin of life. Every living creature on Earth uses the same code, in which DNA 
stores information using four nucleotide bases. The sequences of nucleotides 
encode information for constructing proteins from an alphabet of 20 amino acids.

But why these numbers—four and 20—and not some others? Back in 2000, just a few 
years after Grover published his work, [Apoorva Patel at the Indian Institute 
of Science in Bangalore showed how Grover’s algorithm could explain these 
numbers](https://arxiv.org/abs/quant-ph/0002037).

Patel’s idea is related to the way DNA is assembled inside cells. In this 
situation, the molecular machinery inside a cell must search through the 
molecular soup of nucleotide bases to find the right one. If there are four 
choices, a classical search takes four steps on average. So the machinery would 
have to try four different bases during each assembly step.

But a quantum search using Grover’s algorithm is much quicker: Patel showed 
that when there are four choices, a quantum search can distinguish between four 
alternatives in a single step. Indeed, four is optimal number.

This thinking also explains why there are 20 amino acids. In DNA, each set of 
three nucleotides defines a single amino acid. So the sequence of triplets in 
DNA defines the sequence of amino acids in a protein.

But during protein assembly, each amino acid must be chosen from a soup of 20 
different options. Grover’s algorithm explains these numbers: a three-step 
quantum search can find an object in a database containing up to 20 kinds of 
entry. Again, 20 is the optimal number.

In other words, if the search processes involved in assembling DNA and proteins 
is to be as efficient as possible, the number of bases should be four and the 
number of amino acids should to be 20—exactly as is found. The only caveat is 
that the searches must be quantum in nature.

When Patel published his idea, quantum physicists immediately pooh-poohed it. 
At the time, they were bogged down in their own attempts to control quantum 
processes, which they could do only by isolating quantum particles in extreme 
environments such as at temperatures close to absolute zero.

The obvious problem, they said, was that living things operate in a warm, messy 
environment in which quantum states would be immediately destroyed.

Biologists were equally dismissive, saying that quantum processes couldn’t 
possibly be at work inside living things.

Since then, an increasing body of evidence has emerged that quantum processes 
play an important role in a number of biological mechanisms. Photosynthesis, 
for example, is now thought to be an essentially quantum process.

The work of Guillet and co throws a new perspective on all this. It suggests 
that Grover’s algorithm is not only possible in certain materials; it seems to 
be a property of nature. And if that’s true, then the objections to Patel’s 
ideas start to crumble.

It may be that life is just an example of Grover’s quantum search at work, and 
that this algorithm is itself a fundamental property of nature. That’s a Big 
Idea if ever there was one.

Ref: arxiv.org/abs/1908.11213 : The Grover search as a naturally occurring 
phenomenon

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