Author: kono
Date: 2010-02-11 19:25:46 -0800 (Thu, 11 Feb 2010)
New Revision: 19312

Added:
   
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGEntryType.java
   
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGRelationType.java
   csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/util/
   
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/util/ColorParser.java
   csplugins/trunk/ucsd/kono/KGMLReader/testData/bsu00030.xml
Modified:
   
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/PathwayMapper.java
Log:
New attributes added to nodes.

Added: 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGEntryType.java
===================================================================
--- 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGEntryType.java
                          (rev 0)
+++ 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGEntryType.java
  2010-02-12 03:25:46 UTC (rev 19312)
@@ -0,0 +1,16 @@
+package org.cytoscape.data.reader.kgml;
+
+public enum KEGGEntryType {
+       ORTHOLOG("ortholog"), ENZYME("enzyme"), GENE("gene"), GROUP("group"), 
+       COMPOUND("compound"), MAP("map");
+
+       private String tag;
+       
+       private KEGGEntryType(final String tag) {
+               this.tag = tag;
+       }
+       
+       public String getTag() {
+               return this.tag;
+       }
+}

Added: 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGRelationType.java
===================================================================
--- 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGRelationType.java
                               (rev 0)
+++ 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/KEGGRelationType.java
       2010-02-12 03:25:46 UTC (rev 19312)
@@ -0,0 +1,16 @@
+package org.cytoscape.data.reader.kgml;
+
+public enum KEGGRelationType {
+       EC_REL("ECrel"), PP_REL("PPrel"), GE_REL("GErel"), 
+       PC_REL("PCrel"), MAPLINK("maplink");
+
+       private final String tag;
+       
+       private KEGGRelationType(final String tag) {
+               this.tag = tag;
+       }
+       
+       public String getTag() {
+               return this.tag;
+       }
+}

Modified: 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/PathwayMapper.java
===================================================================
--- 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/PathwayMapper.java
  2010-02-12 01:26:06 UTC (rev 19311)
+++ 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/PathwayMapper.java
  2010-02-12 03:25:46 UTC (rev 19312)
@@ -21,6 +21,7 @@
 import cytoscape.Cytoscape;
 import cytoscape.data.CyAttributes;
 import cytoscape.view.CyNetworkView;
+import cytoscape.visual.ArrowShape;
 import cytoscape.visual.EdgeAppearanceCalculator;
 import cytoscape.visual.GlobalAppearanceCalculator;
 import cytoscape.visual.NodeAppearanceCalculator;
@@ -40,6 +41,14 @@
 
        private int[] nodeIdx;
        private int[] edgeIdx;
+       
+       private static final String KEGG_NAME = "KEGG.name";
+       private static final String KEGG_ENTRY_TYPE = "KEGG.entry";
+       private static final String KEGG_LABEL = "KEGG.label";
+       private static final String KEGG_RELATION_TYPE = "KEGG.relation";
+       
+       
+       private static final String KEGG_LINK = "KEGG.link";
 
        public PathwayMapper(final Pathway pathway) {
                this.pathway = pathway;
@@ -66,8 +75,15 @@
                        if 
(!comp.getGraphics().getType().equals(KEGGShape.LINE.getTag())) {
                                CyNode node = Cytoscape.getCyNode(pathwayID + 
"-"
                                                + comp.getId(), true);
-                               nodeAttr.setAttribute(node.getIdentifier(), 
"KEGG.name", comp
+                               nodeAttr.setAttribute(node.getIdentifier(), 
KEGG_NAME, comp
                                                .getName());
+                               nodeAttr.setAttribute(node.getIdentifier(), 
KEGG_LINK, comp.getLink());
+                               nodeAttr.setAttribute(node.getIdentifier(), 
KEGG_ENTRY_TYPE, comp.getType());
+                               
+                               final Graphics graphics = comp.getGraphics();
+                               if(graphics != null && graphics.getName() != 
null) {
+                                       
nodeAttr.setAttribute(node.getIdentifier(), KEGG_LABEL, graphics.getName());
+                               }
                                nodeMap.put(comp.getId(), node);
                                entryMap.put(comp.getId(), comp);
                        }
@@ -85,6 +101,8 @@
                final List<Relation> relations = pathway.getRelation();
                final List<CyEdge> edges = new ArrayList<CyEdge>();
                
+               final CyAttributes edgeAttr = Cytoscape.getEdgeAttributes();
+               
                for(Relation rel: relations) {
                        final String ent1 = rel.getEntry1();
                        final String ent2 = rel.getEntry2();
@@ -93,14 +111,19 @@
                        final String type = rel.getType();
                        CyNode source = nodeMap.get(ent1);
                        CyNode target = nodeMap.get(ent2);
-                       CyNode compound = nodeMap.get(subs.get(0).getValue());
-                       System.out.println(source.getIdentifier());
-                       System.out.println(target.getIdentifier());
-                       System.out.println(compound.getIdentifier() + "\n\n");
-                       CyEdge edge1 = Cytoscape.getCyEdge(source, compound, 
"interaction", type, true);
-                       CyEdge edge2 = Cytoscape.getCyEdge(compound, target, 
"interaction", type, true);
-                       edges.add(edge1);
-                       edges.add(edge2);
+                       
+                       for(Subtype sub: subs) {
+                               CyNode hub = nodeMap.get(sub.getValue());
+                               System.out.println(source.getIdentifier());
+                               System.out.println(target.getIdentifier());
+                               System.out.println(hub.getIdentifier() + 
"\n\n");
+                               CyEdge edge1 = Cytoscape.getCyEdge(source, hub, 
"interaction", type, true);
+                               CyEdge edge2 = Cytoscape.getCyEdge(hub, target, 
"interaction", type, true);
+                               edges.add(edge1);
+                               edges.add(edge2);
+                               
+                               edgeAttr.setAttribute(edge1.getIdentifier(), 
this.KEGG_RELATION_TYPE, type);
+                       }       
                }
                
                edgeIdx = new int[edges.size()];
@@ -143,18 +166,21 @@
                
nac.getDefaultAppearance().set(VisualPropertyType.NODE_FILL_COLOR,
                                nodeColor);
                nac.getDefaultAppearance().set(VisualPropertyType.NODE_SHAPE,
-                               NodeShape.ELLIPSE);
-               
nac.getDefaultAppearance().set(VisualPropertyType.NODE_BORDER_OPACITY,
-                               220);
+                               NodeShape.ROUND_RECT);
 
                
nac.getDefaultAppearance().set(VisualPropertyType.NODE_BORDER_COLOR,
                                nodeLineColor);
-
+               
nac.getDefaultAppearance().set(VisualPropertyType.NODE_LINE_WIDTH,
+                               2);
+               
                
nac.getDefaultAppearance().set(VisualPropertyType.NODE_LABEL_COLOR,
                                nodeLabelColor);
                
nac.getDefaultAppearance().set(VisualPropertyType.NODE_FONT_FACE,
                                nodeLabelFont);
                
+               //Default Edge appr
+               
eac.getDefaultAppearance().set(VisualPropertyType.EDGE_TGTARROW_SHAPE, 
ArrowShape.DELTA);
+               
                final DiscreteMapping nodeWidth = new DiscreteMapping(30,
                                "ID", ObjectMapping.NODE_MAPPING);
                final Calculator nodeWidthCalc = new BasicCalculator(vsName + 
"-"

Added: 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/util/ColorParser.java
===================================================================
--- 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/util/ColorParser.java
                               (rev 0)
+++ 
csplugins/trunk/ucsd/kono/KGMLReader/src/org/cytoscape/data/reader/kgml/util/ColorParser.java
       2010-02-12 03:25:46 UTC (rev 19312)
@@ -0,0 +1,9 @@
+package org.cytoscape.data.reader.kgml.util;
+
+import java.awt.Color;
+
+public class ColorParser {
+       public static Color getColor(final String colorString) {
+               return null;
+       }
+}

Added: csplugins/trunk/ucsd/kono/KGMLReader/testData/bsu00030.xml
===================================================================
--- csplugins/trunk/ucsd/kono/KGMLReader/testData/bsu00030.xml                  
        (rev 0)
+++ csplugins/trunk/ucsd/kono/KGMLReader/testData/bsu00030.xml  2010-02-12 
03:25:46 UTC (rev 19312)
@@ -0,0 +1,803 @@
+<?xml version="1.0"?>
+<!DOCTYPE pathway SYSTEM "http://www.genome.jp/kegg/xml/KGML_v0.7.0_.dtd";>
+<!-- Creation date: Oct 7, 2009 14:31:05 +0900 (JST) -->
+<pathway name="path:bsu00030" org="bsu" number="00030"
+         title="Pentose phosphate pathway"
+         image="http://www.genome.jp/kegg/pathway/bsu/bsu00030.png";
+         link="http://www.genome.jp/kegg-bin/show_pathway?bsu00030";>
+    <entry id="1" name="cpd:C01151" type="compound"
+        link="http://www.kegg.jp/dbget-bin/www_bget?C01151";>
+        <graphics name="C01151" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="circle" x="692" y="552" width="8" height="8"/>
+    </entry>
+    <entry id="2" name="ko:K05774" type="ortholog" reaction="rn:R06836"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K05774";>
+        <graphics name="K05774" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="628" y="554" width="46" height="17"/>
+    </entry>
+    <entry id="3" name="cpd:C00668" type="compound"
+        link="http://www.kegg.jp/dbget-bin/www_bget?C00668";>
+        <graphics name="C00668" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="circle" x="201" y="303" width="8" height="8"/>
+    </entry>
+    <entry id="4" name="bsu:BSU31350" type="gene" reaction="rn:R02739"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU31350";>
+        <graphics name="pgi" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="258" y="304" width="46" height="17"/>
+    </entry>
+    <entry id="5" name="cpd:C00118" type="compound"
+        link="http://www.kegg.jp/dbget-bin/www_bget?C00118";>
+        <graphics name="C00118" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="circle" x="819" y="303" width="8" height="8"/>
+    </entry>
+    <entry id="6" name="cpd:C00022" type="compound"
+        link="http://www.kegg.jp/dbget-bin/www_bget?C00022";>
+        <graphics name="C00022" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="circle" x="790" y="228" width="8" height="8"/>
+    </entry>
+    <entry id="7" name="bsu:BSU22100" type="gene" reaction="rn:R05605"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU22100";>
+        <graphics name="kdgA" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="752" y="293" width="46" height="17"/>
+    </entry>
+    <entry id="8" name="path:bsu00010" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00010";>
+        <graphics name="Glycolysis / Gluconeogenesis" fgcolor="#000000" 
bgcolor="#FFFFFF"
+             type="roundrectangle" x="994" y="227" width="68" height="26"/>
+    </entry>
+    <entry id="9" name="bsu:BSU35920" type="gene" reaction="rn:R02750"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU35920";>
+        <graphics name="rbsK" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="401" y="612" width="46" height="17"/>
+    </entry>
+    <entry id="10" name="bsu:BSU23500" type="gene" reaction="rn:R02749"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU23500";>
+        <graphics name="drm" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="402" y="644" width="46" height="17"/>
+    </entry>
+    <entry id="11" name="bsu:BSU39420" type="gene" reaction="rn:R01066"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU39420";>
+        <graphics name="deoC" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="262" y="644" width="46" height="17"/>
+    </entry>
+    <entry id="12" name="bsu:BSU00510" type="gene" reaction="rn:R01049"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU00510";>
+        <graphics name="prs" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="529" y="516" width="46" height="17"/>
+    </entry>
+    <entry id="13" name="bsu:BSU23500" type="gene" reaction="rn:R01057"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU23500";>
+        <graphics name="drm" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="628" y="490" width="46" height="17"/>
+    </entry>
+    <entry id="14" name="bsu:BSU35920" type="gene" reaction="rn:R01051"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU35920";>
+        <graphics name="rbsK" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="628" y="469" width="46" height="17"/>
+    </entry>
+    <entry id="15" name="bsu:BSU17890" type="gene" reaction="rn:R01641"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU17890";>
+        <graphics name="tkt" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="420" y="509" width="46" height="17"/>
+    </entry>
+    <entry id="16" name="bsu:BSU36920" type="gene" reaction="rn:R01056"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU36920";>
+        <graphics name="ywlF" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="531" y="434" width="46" height="17"/>
+    </entry>
+    <entry id="17" name="bsu:BSU15790" type="gene" reaction="rn:R01529"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU15790";>
+        <graphics name="rpe" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="476" y="396" width="46" height="17"/>
+    </entry>
+    <entry id="18" name="bsu:BSU17890" type="gene" reaction="rn:R01830"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU17890";>
+        <graphics name="tkt" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="305" y="396" width="46" height="17"/>
+    </entry>
+    <entry id="19" name="bsu:BSU37120" type="gene" reaction="rn:R01070"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU37120";>
+        <graphics name="fbaA" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="200" y="511" width="46" height="17"/>
+    </entry>
+    <entry id="20" name="bsu:BSU29190" type="gene" reaction="rn:R04779"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU29190";>
+        <graphics name="pfkA" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="201" y="435" width="46" height="17"/>
+    </entry>
+    <entry id="21" name="bsu:BSU37090 bsu:BSU40190" type="gene" 
reaction="rn:R04780"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU37090+bsu:BSU40190";>
+        <graphics name="ywjI..." fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="150" y="435" width="46" height="17"/>
+    </entry>
+    <entry id="22" name="bsu:BSU31350" type="gene" reaction="rn:R02740"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU31350";>
+        <graphics name="pgi" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="200" y="349" width="46" height="17"/>
+    </entry>
+    <entry id="23" name="ko:K00032" type="ortholog" reaction="rn:R02032 
rn:R02034"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K00032";>
+        <graphics name="K00032" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="489" y="277" width="46" height="17"/>
+    </entry>
+    <entry id="24" name="ko:K11441" type="ortholog" reaction="rn:R02658"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K11441";>
+        <graphics name="K11441" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="450" y="241" width="46" height="17"/>
+    </entry>
+    <entry id="25" name="bsu:BSU23860 bsu:BSU25730 bsu:BSU40080" type="gene" 
reaction="rn:R01528"
+        
link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU23860+bsu:BSU25730+bsu:BSU40080";>
+        <graphics name="yqjI..." fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="529" y="350" width="46" height="17"/>
+    </entry>
+    <entry id="26" name="bsu:BSU13010" type="gene" reaction="rn:R02035"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU13010";>
+        <graphics name="ykgB" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="472" y="304" width="46" height="17"/>
+    </entry>
+    <entry id="27" name="bsu:BSU23850" type="gene" reaction="rn:R02736"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU23850";>
+        <graphics name="zwf" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="365" y="303" width="46" height="17"/>
+    </entry>
+    <entry id="29" name="bsu:BSU22110" type="gene" reaction="rn:R01541"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU22110";>
+        <graphics name="kdgK" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="691" y="241" width="46" height="17"/>
+    </entry>
+    <entry id="30" name="ko:K01690" type="ortholog" reaction="rn:R02036"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K01690";>
+        <graphics name="K01690" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="608" y="304" width="46" height="17"/>
+    </entry>
+    <entry id="31" name="bsu:BSU40060" type="gene" reaction="rn:R01737"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU40060";>
+        <graphics name="gntK" fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="532" y="241" width="46" height="17"/>
+    </entry>
+    <entry id="32" name="ko:K05308" type="ortholog" reaction="rn:R01538"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K05308";>
+        <graphics name="K05308" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="608" y="156" width="46" height="17"/>
+    </entry>
+    <entry id="33" name="ko:K01053" type="ortholog" reaction="rn:R01519"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K01053";>
+        <graphics name="K01053" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="421" y="156" width="46" height="17"/>
+    </entry>
+    <entry id="34" name="ko:K00117" type="ortholog" reaction="rn:R06620"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K00117";>
+        <graphics name="K00117" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="267" y="214" width="46" height="17"/>
+    </entry>
+    <entry id="35" name="ko:K00115" type="ortholog" reaction="rn:R00305"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K00115";>
+        <graphics name="K00115" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="rectangle" x="267" y="193" width="46" height="17"/>
+    </entry>
+    <entry id="37" name="bsu:BSU02830 bsu:BSU03930" type="gene" 
reaction="rn:R01520 rn:R01521"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu:BSU02830+bsu:BSU03930";>
+        <graphics name="ycdF..." fgcolor="#000000" bgcolor="#BFFFBF"
+             type="rectangle" x="267" y="125" width="46" height="17"/>
+    </entry>
+    <entry id="38" name="path:bsu00010" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00010";>
+        <graphics name="Glycolysis / Gluconeogenesis" fgcolor="#000000" 
bgcolor="#FFFFFF"
+             type="roundrectangle" x="50" y="426" width="64" height="276"/>
+    </entry>
+    <entry id="39" name="path:bsu00040" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00040";>
+        <graphics name="Pentose and glucuronate interconversions" 
fgcolor="#000000" bgcolor="#FFFFFF"
+             type="roundrectangle" x="429" y="356" width="136" height="34"/>
+    </entry>
+    <entry id="40" name="path:bsu00230" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00230";>
+        <graphics name="Purine metabolism" fgcolor="#000000" bgcolor="#FFFFFF"
+             type="roundrectangle" x="635" y="593" width="73" height="32"/>
+    </entry>
+    <entry id="41" name="path:bsu00030" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?pathway+bsu00030";>
+        <graphics name="TITLE:Pentose phosphate pathway" fgcolor="#000000" 
bgcolor="#FFFFFF"
+             type="roundrectangle" x="165" y="58" width="249" height="25"/>
+    </entry>
+    <entry id="42" name="path:bsu00240" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00240";>
+        <graphics name="Pyrimidine metabolism" fgcolor="#000000" 
bgcolor="#FFFFFF"
+             type="roundrectangle" x="635" y="628" width="73" height="32"/>
+    </entry>
+    <entry id="43" name="path:bsu00340" type="map"
+        link="http://www.kegg.jp/dbget-bin/www_bget?bsu00340";>
+        <graphics name="Histidine metabolism" fgcolor="#000000" 
bgcolor="#FFFFFF"
+             type="roundrectangle" x="636" y="663" width="73" height="32"/>
+    </entry>
+    <entry id="45" name="ko:K06151 ko:K06152" type="ortholog" 
reaction="rn:R01741"
+        link="http://www.kegg.jp/dbget-bin/www_bget?K06151+K06152";>
+        <graphics name="K06151..." fgcolor="#000000" bgcolor="#FFFFFF"
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+    </reaction>
+    <reaction name="rn:R01529" type="reversible">
+        <substrate name="cpd:C00199"/>
+        <product name="cpd:C00231"/>
+    </reaction>
+    <reaction name="rn:R01830" type="reversible">
+        <substrate name="cpd:C00118"/>
+        <substrate name="cpd:C05345"/>
+        <product name="cpd:C00279"/>
+        <product name="cpd:C00231"/>
+    </reaction>
+    <reaction name="rn:R01070" type="reversible">
+        <substrate name="cpd:C05378"/>
+        <product name="cpd:C00118"/>
+    </reaction>
+    <reaction name="rn:R04779" type="irreversible">
+        <substrate name="cpd:C05345"/>
+        <product name="cpd:C05378"/>
+    </reaction>
+    <reaction name="rn:R04780" type="irreversible">
+        <substrate name="cpd:C05378"/>
+        <product name="cpd:C05345"/>
+    </reaction>
+    <reaction name="rn:R02740" type="reversible">
+        <substrate name="cpd:C00668"/>
+        <product name="cpd:C05345"/>
+    </reaction>
+    <reaction name="rn:R02032 rn:R02034" type="irreversible">
+        <substrate name="cpd:C00345"/>
+        <product name="cpd:C01218"/>
+    </reaction>
+    <reaction name="rn:R02658" type="irreversible">
+        <substrate name="cpd:C06473"/>
+        <product name="cpd:C01218"/>
+    </reaction>
+    <reaction name="rn:R01528" type="irreversible">
+        <substrate name="cpd:C00345"/>
+        <product name="cpd:C00199"/>
+    </reaction>
+    <reaction name="rn:R02035" type="reversible">
+        <substrate name="cpd:C01236"/>
+        <product name="cpd:C00345"/>
+    </reaction>
+    <reaction name="rn:R02736" type="irreversible">
+        <substrate name="cpd:C01172"/>
+        <product name="cpd:C01236"/>
+    </reaction>
+    <reaction name="rn:R01544" type="irreversible">
+        <substrate name="cpd:C03752"/>
+        <product name="cpd:C00204"/>
+    </reaction>
+    <reaction name="rn:R01541" type="irreversible">
+        <substrate name="cpd:C00204"/>
+        <product name="cpd:C04442"/>
+    </reaction>
+    <reaction name="rn:R02036" type="irreversible">
+        <substrate name="cpd:C00345"/>
+        <product name="cpd:C04442"/>
+    </reaction>
+    <reaction name="rn:R01737" type="irreversible">
+        <substrate name="cpd:C00257"/>
+        <product name="cpd:C00345"/>
+    </reaction>
+    <reaction name="rn:R01538" type="irreversible">
+        <substrate name="cpd:C00257"/>
+        <product name="cpd:C00204"/>
+    </reaction>
+    <reaction name="rn:R01519" type="irreversible">
+        <substrate name="cpd:C00198"/>
+        <product name="cpd:C00257"/>
+    </reaction>
+    <reaction name="rn:R06620" type="irreversible">
+        <substrate name="cpd:C00031"/>
+        <product name="cpd:C00198"/>
+    </reaction>
+    <reaction name="rn:R00305" type="irreversible">
+        <substrate name="cpd:C00031"/>
+        <product name="cpd:C00198"/>
+    </reaction>
+    <reaction name="rn:R01522" type="irreversible">
+        <substrate name="cpd:C00221"/>
+        <product name="cpd:C00198"/>
+    </reaction>
+    <reaction name="rn:R01520 rn:R01521" type="reversible">
+        <substrate name="cpd:C00221"/>
+        <product name="cpd:C00198"/>
+    </reaction>
+    <reaction name="rn:R01522" type="irreversible">
+        <substrate name="cpd:C00221"/>
+        <product name="cpd:C00198"/>
+    </reaction>
+    <reaction name="rn:R01741" type="irreversible">
+        <substrate name="cpd:C00257"/>
+        <product name="cpd:C06473"/>
+    </reaction>
+    <reaction name="rn:R01827" type="reversible">
+        <substrate name="cpd:C05382"/>
+        <substrate name="cpd:C00118"/>
+        <product name="cpd:C00279"/>
+        <product name="cpd:C05345"/>
+    </reaction>
+    <reaction name="rn:R01057" type="reversible">
+        <substrate name="cpd:C00620"/>
+        <product name="cpd:C00117"/>
+    </reaction>
+    <reaction name="rn:R06837" type="reversible">
+        <substrate name="cpd:C00620"/>
+        <product name="cpd:C01151"/>
+    </reaction>
+    <reaction name="rn:R08570" type="reversible">
+        <substrate name="cpd:C00204"/>
+        <product name="cpd:C00022"/>
+        <product name="cpd:C00577"/>
+    </reaction>
+    <reaction name="rn:R08571" type="irreversible">
+        <substrate name="cpd:C00577"/>
+        <product name="cpd:C00258"/>
+    </reaction>
+    <reaction name="rn:R08572" type="irreversible">
+        <substrate name="cpd:C00258"/>
+        <product name="cpd:C00631"/>
+    </reaction>
+    <reaction name="rn:R05605" type="reversible">
+        <substrate name="cpd:C04442"/>
+        <product name="cpd:C00022"/>
+        <product name="cpd:C00118"/>
+    </reaction>
+    <reaction name="rn:R01739" type="reversible">
+        <substrate name="cpd:C00257"/>
+        <product name="cpd:C06473"/>
+    </reaction>
+    <reaction name="rn:R01621" type="irreversible">
+        <substrate name="cpd:C00231"/>
+        <product name="cpd:C00118"/>
+    </reaction>
+</pathway>

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