Here's what I experienced was that after a distr-update which included
libgdk-pixbuf2.0-0:amd (from 2.30.7-1 to 2.30.8-1). I received the warning that
the install was likely broken, and tried the recommendation (below) which
failed.
"/usr/lib/gdk-pixbuf-2.0/gdk-pixbuf-query-loaders >
/usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache"
The problem was that the command itself ('gdk-pixbuf-query-loaders') was
broken. (If you open it, it will tell you it is is broken, can't save, failed
sanity check, etc.) So in terminal mode, as I couldn't get a gui,
I used dpkg-reconfigure libgdk-pixbuf2.0-0:amd64 and for good measure
dpkg-reconfigure gir1.2-gdkpixbuf-2.0:amd64, rebooted, and voila back to normal.
I hope this is helpful!
Cheers!