This is caused by the following backward incompatible change in GNU 4.3:

https://lists.gnu.org/archive/html/info-gnu/2020-01/msg00004.html

* WARNING: Backward-incompatibility!
  Previously appending using '+=' to an empty variable would result in a
value
  starting with a space.  Now the initial space is only added if the
variable
  already contains some value.  Similarly, appending an empty string does
not
  add a trailing space.

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