As there were several changes in 5.10.140 to the kernel I/O code which
could be the cause of my issue, I downloaded the vanilla source code for
the 5.10.139 kernel and built it using my Debian kernel config from /boot.
I installed the resulting kernel and kernel headers and DKMS built the
required ZFS modules. Upon rebooting, all my ZFS pools are working as
expected.

In particular, the main pool that consistently showed six missing drives
(A1-A6) under 5.10.140 is now showing all drives as online, just as it does
with 5.10.136-1.  In total, this system has 48 3.5" 7200 RPM SATA drives,
two 1.92TB Samsung enterprise SATA SSDs, and three NVMe SSDs.  The impacted
drives are 16TB 3.5" drives, which are in two 4U DS4246 JBOD enclosures,
and attached to a Dell R730xd server via an LSI 9207-8e HBA running P20
firmware in IT mode.  I'm running ZFS 2.1.5 from bullseye-backports.  Note
that SMART data for the impacted drives is normal with no bad sectors.  The
only change I made was booting into a different kernel.  Otherwise, it's
running all the updates from the 11.5 point release.

I will try to bisect 5.10.140 tomorrow to determine more precisely which
commit(s) are causing my issue.

        NAME                                             STATE     READ
WRITE CKSUM
        data                                             ONLINE       0
0     0
          raidz2-0                                       ONLINE       0
0     0
            A1                                           ONLINE       0
0     0
            A2                                           ONLINE       0
0     0
            A3                                           ONLINE       0
0     0
            A4                                           ONLINE       0
0     0
            A5                                           ONLINE       0
0     0
            A6                                           ONLINE       0
0     0
            A7                                           ONLINE       0
0     0
            A8                                           ONLINE       0
0     0
            A9                                           ONLINE       0
0     0
            A10                                          ONLINE       0
0     0
            A11                                          ONLINE       0
0     0
            A12                                          ONLINE       0
0     0
        special
          mirror-1                                       ONLINE       0
0     0
            nvme-HP_SSD_EX920_1TB_HBSE48481800144-part1  ONLINE       0
0     0
            nvme-HP_SSD_EX920_1TB_HBSE48481800847-part1  ONLINE       0
0     0
        logs
          mirror-2                                       ONLINE       0
0     0
            nvme-HP_SSD_EX920_1TB_HBSE48481800144-part2  ONLINE       0
0     0

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