Hello there, thanks for reassigning the bug report.
Indeed, Ptyxis is not responsible for anything, but it's the only
program that could output something searchable, like an error that I've
included in the original post. Nautilus stops working as well.
I've tried using Chromium (taken from the stable repository), and it
also seems to be encountering the same issue, except it actually
complains about profiles (forgotten the details, but I can try to
replicate it again).
About an issue with my hardware... I think that's out of the question -
SMART logs look alright to me, there are no errors.
Sorry if I'm doing anything wrong right now - this is my first time
filing a bug report