Package: wnpp Severity: wishlist Owner: Laszlo Kajan <lka...@rostlab.org>
* Package name : hhsuite Version : 2.0.4 Upstream Author : Johannes Soeding, Michael Remmert, Andreas Hauser <hau...@genzentrum.lmu.de>, Andreas Biegert * URL : http://toolkit.genzentrum.lmu.de/sections/search * License : GPLv3 Programming Lang: C++ Description : sensitive protein sequence searching based on HMM-HMM alignment The HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). It contains HHsearch and HHblits among other programs and utilities. . HHsearch takes as input a multiple sequence alignment (MSA) or profile HMM and searches a database of HMMs (e.g. PDB, Pfam, or InterPro) for homologous proteins. HHsearch is often used for protein structure prediction to detect homologous templates and to build highly accurate query-template pairwise alignments for homology modeling. . HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and, using an iterative search strategy, adds significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. -- To UNSUBSCRIBE, email to debian-bugs-dist-requ...@lists.debian.org with a subject of "unsubscribe". Trouble? Contact listmas...@lists.debian.org
