I did some more tests

I moved the following to a backup location:
   ~/.icedove
   ~/.thunderbird
   ~/.cache/icedove

so it should create a completely new profile.

Then I run it in safe mode to avoid any plugins:

$ icedove -safe-mode

The main window appears but it is unresponsive to any mouse clicks on
any of the buttons or menus.  I looked for any modal popup windows or
dialogs that may have blocked mouse clicks on the main window but I
couldn't find any.

I attach a screenshot.  The console output is:

$ icedove -safe-mode

(process:7319): GLib-CRITICAL **: g_slice_set_config: assertion
'sys_page_size == 0' failed
TypeError: nounDef is undefined
-- Exception object --
*
-- Stack Trace --
gloda_ns_newQuery@resource:///modules/gloda/gloda.js:1897:5
ContactIdentityCompleter@resource://gre/components/glautocomp.js:178:7
nsAutoCompleteGloda@resource://gre/components/glautocomp.js:493:5
XPCOMUtils__getFactory/factory.createInstance@resource://gre/modules/XPCOMUtils.jsm:271:11
glodaSearch_XBL_Constructor@chrome://messenger/content/search.xml:75:1




I used strace to capture all activity during startup and tried to work
out what else it may have been looking for in $HOME.  There were over
1500 references to distinct files in $HOME

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