Hi Martin,

First off, thanks for all your work on last-align upstream! :-)
See below:

On Tue, 22 Dec 2020 at 13:46, Frith, Martin <[email protected]>
wrote:

> Many thanks for this detailed problem report.
>
> I believe that's an unintended (and surprising) problem, it should still
> work. The trouble is, it works on all my computers (I don't have a 32-bit
> arch). So it's hard for me to figure out.
>

You can maybe create an i386 chroot in an amd64 system, and test stuff
there - this is how I'm testing it as well.


>
> If you replace your command with:
> $lastal -vvv humdb fuguMito.fa
> (verbose mode), what does it print before hanging?
>

$lastal -vvv humdb fuguMito.fa
/usr/lib/last-align/lastal-plain: batch size=8192
/usr/lib/last-align/lastal-plain: calculating matrix probabilities...
/usr/lib/last-align/lastal-plain: matrix lambda=1.09861
/usr/lib/last-align/lastal-plain: matrix letter frequencies
(upper=reference, lower=query):
A   C   G   T
25  25  25  25
25  25  25  25
/usr/lib/last-align/lastal-plain: getting E-value parameters...
1.0960171987681839, 0.33538787507026158,
2.0290734315292083, -0.46514786408422282,
2.0290734315292083, -0.46514786408422282,
5.0543294182155085, 15.130999712620039,
5.0543294182155085, 15.130999712620039,
5.0543962679167036, 15.129930117400917

Hangs after this bit.


>
> It would be great if you could test versions between 1145 and 1167 (e.g.
> by "hg update -r1155"). Of course I can't expect you to go to that trouble.
>

 I tried it for version 1155, and it times out with the exact same log I
pasted above for 1167. Which means something broke between 1145 -1155.
Admittedly, I did not inspect any further.

Please let me know if you'd need any more information.

Thanks and regards

Nilesh

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