I have adopted this workaround: copy gtk-3.0 specific setting to inkscape config subdir: cp -a ~/.config/gtk-3.0 ~/.config/inkscape/
editing file ~/.config/inkscape/gtk-3.0/settings.ini comment line: ; gtk-font-name=Noto Sans 10 modify command start application in: XDG_CONFIG_HOME=/home/root/.config/inkscape inkscape Now inkscape works, without making changes to the system. However, I disabled the preview of the fonts because it takes too long. Antonio