I have adopted this workaround:

copy gtk-3.0 specific setting to inkscape config subdir:
cp -a ~/.config/gtk-3.0 ~/.config/inkscape/

editing file ~/.config/inkscape/gtk-3.0/settings.ini

comment line:
; gtk-font-name=Noto Sans 10

modify command start application in:
XDG_CONFIG_HOME=/home/root/.config/inkscape inkscape

Now inkscape works, without making changes to the system.
However, I disabled the preview of the fonts because it takes too long.
Antonio

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