Package: wnpp Owner: "Debian Ruby Team" <debian-ruby@lists.debian.org> Severity: wishlist X-Debbugs-CC: debian-ruby@lists.debian.org
* Package name : ruby-crb-blast Version : 0.6.4 Upstream Author : Chris Boursnell & Richard Smith-Unna * URL : https://github.com/cboursnell/crb-blast * License : MIT Programming Lang: Ruby Description : Run conditional reciprocal best blast CRB-BLAST is a novel method for finding orthologs between one set of sequences and another. This is particularly useful in genome and transcriptome annotation. CRB-BLAST initially performs a standard reciprocal best BLAST. It does this by performing BLAST alignments of query->target and target->query. Reciprocal best BLAST hits are those where the best match for any given query sequence in the query->target alignment is also the best hit of the match in the reverse (target->query) alignment. Reciprocal best BLAST is a very conservative way to assign orthologs. The main innovation in CRB-BLAST is to learn an appropriate e-value cutoff to apply to each pairwise alignment by taking into account the overall relatedness of the two datasets being compared. This is done by fitting a function to the distribution of alignment e-values over sequence lengths. The function the e-value cutoff for a sequence of given length. This package is a dependency for 'transrate' This package will be maintained as part of the Debian Ruby packaging team.
