Richard, I managed to build denemo with mxe using 64bit target. It is using guile 3.0.7 because I had trouble getting the lesser versions compiled. Here is the link. I compiled with --enable-debug which should add the -g and -O0 to the compiler. I had trouble debugging it mostly because I don't know what I am doing with wine-dbg. https://www.denemo.org/~jjbenham/denemo-snapshot/denemo-2023-11-19.zip
Thanks, Jeremiah