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https://issues.apache.org/jira/browse/HTTPCLIENT-2024?page=com.atlassian.jira.plugin.system.issuetabpanels:comment-tabpanel&focusedCommentId=17285297#comment-17285297
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Carter Kozak commented on HTTPCLIENT-2024:
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Http/1.1 considers connections persistent unless they provide a connection: 
close header. All servers I’m familiar with follow this behavior, however if 
there’s one that does not, I’d recommend setting the connection pool “validate 
after inactivity” interval to zero or disable pooling altogether. This may have 
severe performance implications especially if you’re using TLS.

> NoHttpResponseException on high Load
> ------------------------------------
>
>                 Key: HTTPCLIENT-2024
>                 URL: https://issues.apache.org/jira/browse/HTTPCLIENT-2024
>             Project: HttpComponents HttpClient
>          Issue Type: Bug
>          Components: HttpClient (classic)
>    Affects Versions: 4.5.7
>            Reporter: shatk
>            Priority: Major
>              Labels: camel-http4,, http-client
>
>  
> Getting _NoHttpResponseException : host:port failed to respond_  on high 
> Load. 
> This is happening for httpclient-4.5.7  as well as httpclient-4.5.10  version 
> of apache http client on high load [100 TPS]
>  Apache http client is used internally by camel http4. 
> [https://github.com/HydAu/Camel/blob/master/components/camel-http4/src/main/java/org/apache/camel/component/http4/HttpComponent.java]
>  > camel http4 connection config :
> connectionsPerRoute : 100
> maxTotalConnections : 1000 
>  
>  
>  
>  



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