Latency/timeout changes when upgrading client from 4 to 5

[Ryan Schmitt]

On Saturday we rolled out a company-wide upgrade from Apache client 4.5.13
to 5.0.3, and yesterday we ended up rolling it back due to several services
reporting significant increases in client-side latency and request failures
due to NoHttpResponseException. Can someone suggest a good place to start
looking for the root cause?