On Wednesday, 1 September 2021 at 05:27:38 UTC, James Blachly wrote:
I'm delighted to finally post an official announcement of our package for high-throughput sequencing (HTS), also called Next-generation sequencing (NGS): `dhtslib`. It's not a very clever name, and we are working on a new one. ;)

https://github.com/blachlylab/dhtslib/

[...]

[2] Here is a contemporary example of D used in high-throughput sequencing: DENTIST by Arne Ludwig at Max Planck institute
    https://github.com/a-ludi/dentist

I am surprised to see the use of DMD (see the Dockerfile). If you want runtime performance, the first thing I would do is switch to LDC or GDC.

Perhaps DENTIST's particular use of D and dhtslib is mainly forwarding calls to htslib (C) and thus D performance is not relevant?

-Johan



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