I experimented with VoiceOver and the latest Opera development build 4669:
http://my.opera.com/macteam/blog/2008/02/22/new-kestrelsnapshot-4669
It appears that the major bug I reported with reading blocks has been fixed:
http://my.opera.com/community/forums/topic.dml?id=203373
I've now reported a different bug, which is that when reading down the
page with control option down the VoiceOver cursor skips over lots of
content:
http://my.opera.com/community/forums/topic.dml?id=224497
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Benjamin Hawkes-Lewis