Chuck,
It's funny you should ask this question today. There was a Hot News
flash from Apple about this very subject. I've included it below
along with a link.
While it was already a great tool for reading PDFs, Preview in Leopard
became even better with new features that include a new user
interface, relevancy ranked searches (thanks to Spotlight), and many
more. In fact, Preview now lets you annotate PDFs, offering a fast and
efficient way to share comments with those you’re collaborating with.
Find out how by reading our Pro Tip of the Week.
Read more…
http://www.apple.com/pro/tips/pdf_annotation.html?sr=hotnews
Marshall