Thanks for posting this. You are right -- OSX is not an easy platform for development, because apple has nothing akin to apt-get. (Why they have not done this, I cannot guess. Surely it cannot be because people find macports and fink to be reliable and useful.)
A couple of points: 1. I found that: sudo easy_install mysql-python worked well, which saves a bit of editing and compiling. 2. Using this (at least with fastcgi) is problematic, because the webserver user ("_www" on OSX) tries to write eggs to locations in which it lacks permissions. I guess the solution is to add the following: os.environ['PYTHON_EGG_CACHE'] = "..." to the fastcgi script, in which the ... is replaced with something that is sensible and safe. But I'm not too sure what is sensible (e.g. things in /tmp get erased by cron jobs) and I certainly have no idea what is safe, so I punted and switched to sqlite3, which seems to work well. 3. A DMG would be terrific. Thanks much for posting this.
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