Introduction to bioinformatics for DNA and RNA sequence analysis (IBDR01)

https://www.prinformatics.com/course/introduction-to-bioinformatics-for-dna-
and-rna-sequence-analysis-ibdr01/

This course will be delivered by Malachi and Obi Griffith in Glasgow City 
centre from 29th October - 2nd November 2018.

Course Overview:
Analysis of high throughput genome and transcriptome data is major 
component of many research projects ranging from large-scale precision 
medicine efforts to focused investigations in model systems. This analysis 
involves the identification of specific genome or transcriptome features 
that predispose individuals to disease, predict response to therapies, 
influence diagnosis/prognosis, or provide mechanistic insights into disease 
models. During this course (PMBI01), students will perform an example end-
to-end bioinformatics analysis of genome (WGS and Exome) and transcriptome 
(RNA-seq) data. Students will start with raw sequence data for a 
hypothetical case, learn to install and use the tools needed to analyze 
this data on the cloud, and visualize and interpret results. After 
completing the course, students should be in a position to (1) understand 
raw sequence data formats, (2) perform bioinformatics analyses on the 
cloud, (3) run complete analysis pipelines for alignment, variant calling, 
annotation, and RNA-seq (transcriptome analysis approaches will be a major 
component of the workshop), (4) visualize and interpret whole genome, exome 
and RNA-seq results, (5) leverage the identification of passenger variants 
for immunotherapy applications, and (6) begin to place these results in a 
clinical context by use of variant knowledgebases. The data, tools, and 
analysis will be most directly relevant to human genomics and 
bioinformatics research. However, many of the skills and concepts covered 
will be applicable to other human diseases and model organisms. 
Furthermore, many analysis concepts covered during the workshop will be 
broadly applicable to other “big data” research problems. All course 
materials (including copies of presentations, practical exercises, data 
files, and example scripts prepared by the instructing team) will be 
provided electronically to participants.

Intended Audience
This workshop is primarily aimed at researchers and technical workers with 
a background in biology who want to learn fundamental bioinformatics skills 
for genomics with a particular emphasis on biomedical research 
applications. The course is essentially a crash course in bioinformatics 
for next generation sequence data analysis. It would also be useful for 
students with a computational background who seek an introduction to 
genomics technology and analysis approaches. In general, it is suitable for 
anyone working with genome or transcriptome (RNA-seq) data in the context 
of disease research. Attendees are encouraged to bring their own data or 
project outlines for discussion. Some time during the course will be 
dedicated to consultation with a team of instructors from the McDonnell 
Genome Institute.

Email oliverhoo...@prinformatics.com
Check out our sister sites,
www.PRstatistics.com (Ecology and Life Sciences)
www.PRinformatics.com (Bioinformatics and data science)
www.PSstatsistics.com (Behaviour and cognition) 


1.      May 7th – 11th 2018 ADVANCES IN MULTIVARIATE ANALYSIS OF SPATIAL 
ECOLOGICAL DATA USING R (MVSP02)
Canada (QUEBEC), Prof. Pierre Legendre, Dr. Guillaume Blanchet
www.prstatistics.com/course/advances-in-spatial-analysis-of-multivariate-
ecological-data-theory-and-practice-mvsp03/

2.      May 14th - 18th 2018
INTRODUCTION TO MIXED (HIERARCHICAL) MODELS FOR BIOLOGISTS (IMBR01)
Canada (QUEBEC), Prof. Subhash Lele 
www.prstatistics.com/course/introduction-to-mixed-hierarchical-models-for-
biologists-using-r-imbr01/

3.      May 21st - 25th 2018
INTRODUCTION TO PYTHON FOR BIOLOGISTS (IPYB05)
Glasgow, Scotland, Dr. Martin Jones
http://www.prinformatics.com/course/introduction-to-python-for-biologists-
ipyb05/

4.      May 21st - 25th 2018
INTRODUCTION TO REMOTE SENISNG AND GIS FOR ECOLOGICAL APPLICATIONS (IRMS01)
Glasgow, Scotland, Prof. Duccio Rocchini, Dr. Luca Delucchi
www.prinformatics.com/course/introduction-to-remote-sensing-and-gis-for-
ecological-applications-irms01/

5.      May 28th – 31st 2018
STABLE ISOTOPE MIXING MODELS USING SIAR, SIBER AND MIXSIAR (SIMM04)
Canada (QUEBEC) Dr. Andrew Parnell, Dr. Andrew Jackson 
www.prstatistics.com/course/stable-isotope-mixing-models-using-r-simm04/

6.      May 28th – June 1st 2018
ADVANCED PYTHON FOR BIOLOGISTS (APYB02)
Glasgow, Scotland, Dr. Martin Jones
www.prinformatics.com/course/advanced-python-biologists-apyb02/

7.      June 12th - 15th 2018
SPECIES DISTRIBUTION MODELLING (DBMR01)
Myuna Bay sport and recreation, Australia, Prof. Jane Elith, Dr. Gurutzeta 
Guillera
www.prstatistics.com/course/species-distribution-models-using-r-sdmr01/

8.      June 25th – 29th 2018
SPECIES DISTRIBUTION/OCCUPANCY MODELLING USING R (OCCU01)
Glasgow, Scotland, Dr. Darryl McKenzie (PROTEUS)
www.prstatistics.com/course/species-distributionoccupancy-modelling-using-r-
occu01/

9.      July 2nd - 5th 2018
SOCIAL NETWORK ANALYSIS FOR BEHAVIOURAL SCIENTISTS USING R (SNAR01)
Glasgow, Scotland, Prof. James Curley
http://www.psstatistics.com/course/social-network-analysis-for-behavioral-
scientists-snar01/

10.     July 8th – 12th 2018
MODEL BASE MULTIVARIATE ANALYSIS OF ABUNDANCE DATA USING R (MBMV02)
Glasgow, Scotland, Prof. David Warton
www.prstatistics.com/course/model-base-multivariate-analysis-of-abundance-
data-using-r-mbmv02/

11.     July 23rd – 27th 2018
EUKARYOTIC METABARCODING (EUKB01)
Glasgow, Scotland, Dr. Owen Wangensteen
http://www.prinformatics.com/course/eukaryotic-metabarcoding-eukb01/

12.     October 1st – 5th 
Introduction to Linux workflows for biologists (IBUL03)
Glasgow, Scotland, Dr. Martin Jones
https://www.prinformatics.com/course/introduction-to-linux-workflows-for-
biologists-ibul03/

13.     October 8th – 12th 2018
INTRODUCTION TO SPATIAL ANALYSIS OF ECOLOGICAL DATA USING R (ISAE01)
Glasgow, Scotland, Prof. Subhash Lele
https://www.prstatistics.com/course/introduction-to-spatial-analysis-of-
ecological-data-using-r-isae01/

14.     October 8th – 12th 2018
INDIVIDUAL BASED MODELS USING NETLOGO AND R
Glasgow, Scotland, Dr. Andrew Jackson
Link to follow

15.     October 15th – 19th 2018
APPLIED BAYESIAN MODELLING FOR ECOLOGISTS AND EPIDEMIOLOGISTS (ABME
Glasgow, Scotland, Dr. Matt Denwood, Emma Howard
http://www.prstatistics.com/course/applied-bayesian-modelling-ecologists-
epidemiologists-abme04/

16.     October 15th – 19th 2018
ANALYSING TIME TO EVENT DATA (SURVIVAL ANALYSIS)
Glasgow, Scotland, Dr. Wil Hoppitt
Link to follow

17.     October 29th – November 2nd 2018
INTRODCUTION TO R AND STATISTICS FOR BIOLOGISTS (IRFB02)
Glasgow, Scotland, Dr. Olivier Gauthier
Link to follow – see previous 
https://www.prstatistics.com/course/introduction-to-statistics-and-r-for-
biologists-irfb/

18.     October 29th – November 2nd 2018
PRECISION MEDICINE BIOINFORMATICS: FROM RAW GENOME AND TRANSCRIPTOME DATA 
TO CLINICAL INTERPRETATION (PMBI01)
Glasgow, Scotland, Dr Malachi Griffith, Dr. Obi Griffith
www.prinformatics.com/course/precision-medicine-bioinformatics-from-raw-
genome-and-transcriptome-data-to-clinical-interpretation-pmbi01/

19.     November 5th – 8th  2018
PHYLOGENETIC COMPARATIVE METHODS FOR STUDYING DIVERSIFICATION AND 
PHENOTYPIC EVOLUTION (PCME01)
Glasgow, Scotland, Dr. Antigoni Kaliontzopoulou
https://www.prstatistics.com/course/phylogenetic-comparative-methods-for-
studying-diversification-and-phenotypic-evolution-pcme01/

20.     November 19th – 23rd  2018
STRUCTUAL EQUATION MODELLING FOR ECOLOGISTS AND EVOLUTIONARY BIOLOGISTS 
(SEMR02)
Glasgow, Scotland, Dr. Jonathan Lefcheck
Link to follow – see previous 
https://www.prstatistics.com/course/structural-equation-modelling-for-
ecologists-and-evolutionary-biologists-semr01/

21.     November 26th – 30th 2018
FUNCTIONAL ECOLOGY FROM ORGANISM TO ECOSYSTEM: THEORY AND COMPUTATION (FEER
Glasgow, Scotland, Dr. Francesco de Bello, Dr. Lars Götzenberger, Dr. 
Carlos Carmona
http://www.prstatistics.com/course/functional-ecology-from-organism-to-
ecosystem-theory-and-computation-feer01/

22.     February 2018 TBC
MOVEMENT ECOLOGY (MOVE02)
Venue TBC, Dr. Luca Borger, Prof. Ronny Wilson, Dr Jonathan Potts
Link to follow – see previous 
www.prstatistics.com/course/movement-ecology-move01/

23.     February 2018 TBC
AQUATIC ACOUSTIC TELEMETRY DATA ANALYSIS AND SURVEY DESIGN
Glasgow, Scotland, VEMCO staff and affiliates
Link to follow

Oliver Hooker PhD.
PR informatics

2018 publications - 

Phenotypic and resource use partitioning amongst sympatric lacustrine brown 
trout, Salmo trutta. Biological Journal of the Linnean Society. DOI 
10.1093/biolinnean/bly032

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