On 17 Jun 2001 04:34:26 -0700, [EMAIL PROTECTED] (Marc)
wrote:

> I have to summarize the results of some clinical trials.
> Unfortunately the reported information is not complete.
> The information given in the trials contain:
> 
> (1) Mean effect in the treatment group (days of hospitalization)
> 
> (2) Mean effect in the control group (days of hospitalization)
> 
> (3) Numbers of patients in the control and treatment group
> 
> (4) p-values of a t-test (between the differences of treatment
>     and control)
> My question:
> How can I calculate the variance of treatment difference which I need
> to perform meta-analysis? Note that the numbers of patients in the

Aren't you going too far?  You said you have to summarize.
Well, summarize.  The difference is in terms of days.  
Or it is in terms of percentage of increase.

And you have the t-test and p-values.  

You might be right in what you propose, but I think
you are much more likely to produce a useful report 
if you keep it simple.

You are right; meta-analyses are complex.  And a 
majority of the published ones are (in my opinion) awful.
--
Rich Ulrich, [EMAIL PROTECTED]
http://www.pitt.edu/~wpilib/index.html


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