Herman Rubin wrote:
> 
> In article <[EMAIL PROTECTED]>,
> Frank E Harrell Jr  <[EMAIL PROTECTED]> wrote:
> >To suggest that ANY method of modeling or data analysis can reliably infer causation
> >from non-experimental data is bogus.  Even in a parallel group double blind
> >randomized controlled trial, in which there is tight experimental manipulation,
> >an assumption is required to infer causation due to treatment effects, for
> >individual patients.
> 
> This is hardly the case.  One does infer causation in such
> fields as geology, astronomy, and meteorology, and also in
> archaeology and paleontology.  It is even done in linguistics.
> 
> How reliable it is does vary from field to field, but it
> not only can be done, but should.  It takes a more careful
> decision-theoretic analysis, but one can only act on the
> available information, and often one must act.

It's hard to disagree with either statement.  The problem is 
what we infer from "infer".  Once upon a time, a key reference
in this area was David Kenny's Correlation & Causality.  Today,
I believe many practitioners look to Kenneth Bollen's Structural
Equations With Latent Variables.  It's been a few years since
I read it, but the two things that stick with me are Figure 3.9
showing 10 different models for three observed variables that
have perfect fit to a particular covariance matrix and Bollen's
statement on page 72, "We can only reject a model--we can never 
prove it to be valid."  Thus, I agree with Harrell that 
statistical methods alone can never "reliably infer" (prove)
causality, but I also agree with Rubin that statistical evidence 
is an important piece of the puzzle when trying to infer (seeing whether
the data are consistent with) a causal relationship.  Try
as I might I can't stop the urge to rephrase the last part of the 
last sentence to, "(seeing whether the data are not inconsistent
with all of the implications of)".  In my experience, I tend to 
see people use the word infer in the sense of "prove".  My
canned response is that statistical methods alone can never prove
*anything*.


never prove caus


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