dennis roberts wrote:
> thus ... when we spend all this time on debating the usefulness or lack of
> usefulness of a p value ... whether it be the .05 level or ANY other ... we
> are totally ignoring the fact that this p value that is reported ... could
> have been the result of many factors having NOTHING to do with sampling
> error ... and nothing to do with the treatments ...
>From my class notes....
100% of all disasters are failures of design, not analysis.
-- Ron Marks, Toronto, August 16, 1994
To propose that poor design can be corrected by subtle analysis
techniques is contrary to good scientific thinking.
-- Stuart Pocock (Controlled Clinical Trials, p 58) regarding the
use of retrospective adjustment for trials with historical controls.
Issues of design always trump issues of analysis.
-- GE Dallal, 1999, explaining why it would be wasted effort to
focus on the analysis of data from a study under challenge whose
design was fatally flawed.
Bias dominates variability.
-- John C. Bailler, III, Indianapolis, August 14, 2000
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