separately posted to sci.stat.consult, sci.stat.edu
On Mon, 25 Dec 2000 17:51:14 +0800, Wen-Feng Hsiao
<[EMAIL PROTECTED]> wrote:

> Dear all,
> 
> Paired t-test helps us to exam whether the paired samples (or the same 
> samples) respond differently between two treatments. The null hypothesis 
> is H0: mu1=mu2 or mu1-mu2=0. Could this be extended to test a null 
> hypothesis with H0: mu1-mu2=C, where C is a constant, but unknown. How? 

Your regular, paired t-test lets you draw the Confidence interval for
the difference.  Does it include 0?  Does it include C?  - not much of
an extension.

> My intention is to show that the treatment effect only affects the shift, 
> but not the shape of the distribution as the following ASCII-graph.

I hope I am not reading the wrong thing into the question here, 
but I was once baffled by a similar problem.
I will re-state the question, in the way that it has confronted me.
I have never seen a good answer - one that I would 
convince everyone else.

Here is my own numeric version for Pre-Post scores, 
instead of an ASCII picture.
  Model A:  scores (1,2,3,4,5)  are  *shifted*  by 3 points each, to
(4,5,6,7,8).
  Model B:  scores (1,2,3,4,5)  are each expanded 3-fold, to
(3,6,9,12,15).

Descriptively:  Model B is "wider"  at Post than at Pre; the variance
of change scores is correlated with the scores.

Unfortunately, that conclusion, or description, is not scale-free.
Once you take the logarithm for data in Model B, Model B would be
"shifted", not expanded.  
 - for small sets of data, you can't tell anything apart.
 - for larger sets, I think you can compare the number of scores
at the low end.  It does depend on the mechanism that you assume is
generating the numbers.  However, I have seen data where (I thought)
the bottom end showed "shift"  because of how thin one density was.


-- 
Rich Ulrich, [EMAIL PROTECTED]
http://www.pitt.edu/~wpilib/index.html


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