On Fri, 28 Jun 2002 16:46:42 -0400
Rich Ulrich <[EMAIL PROTECTED]> wrote:


> Hotelling's one-sample T  would test the totally unfocused hypotheses,
> "any-odd patterns of change"  whatsoever.  Probably, it is
> *not*   going to assume that the 17 Likert items were measured
> in the same units, or change in the same direction.  But I am 
> not positive about that.
> 
> Since I have read a lot about complicated multivariate analyses,...
> I try to avoid any and all of them, whenever possible.  They usually
> waste statistical power, compared to careful planning;  and it 
> is surprisingly difficult to keep track of what any program 
> is supposed to do (and then, be sure that it really does it).
> 
> I hope this expression of opinion is helpful.
> -- 

Rich said it well.  To get a more powerful and focused single test for all items you 
might consider

@ARTICLE{obr84pro,
  author = {O'Brien, Peter C.},
  year = 1984,
  title = {Procedure for comparing samples with multiple endpoints},
  journal = Biometrics,
  volume = 40,
  pages = {1079-1087},
  note = {Errata Biometrics 51:1580-1581; 1995},
  annote = {multiple events; multivariate response; study design;}
}
@ARTICLE{leh94com,
  author = {Lehmacher, Walter and Wassmer, Gernot and Reitmeir, Peter},
  year = 1994,
  title = {Comment on: {On} the design and analysis of randomized clinical
          trials with multiple endpoints},
  journal = Biometrics,
  volume = 50,
  pages = {581-583},
  annote = {multiple endpoints; study design; O'Brien multiple endpoint test}
}
@ARTICLE{obr97int,
  author = {{O'Brien}, Peter C. and Geller, Nancy L.},
  year = 1997,
  title = {Interpreting tests for efficacy in clinical trials with multiple
          endpoints},
  journal = Controlled Clinical Trials,
  volume = 18,
  pages = {222-227},
  annote = {multiple endpoints;study design;innapropriate use of multiple
           endpoint statistical methods}
}


-- 
Frank E Harrell Jr              Prof. of Biostatistics & Statistics
Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences
U. Virginia School of Medicine  http://hesweb1.med.virginia.edu/biostat
.
.
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