Dear all, we conducted a study to determine the prevalence of leukemia in a population. That's a retrospective study collecting the information for people living in an area from 70s. Until now we have 58% of respondant, and we think all cases of leukemia. 10% are definitly lost, 10% could be found but not easily, 20% refuse to answer. We know that the 10% that could be found have no leukemia actually (could have one before). The problem is when we look at the SMR in this 58%, we get a significant RR=6. If we add the 10% that we could found and supposing they never had a leukemia then the RR is borderline significant and = to 4. So my question is: Can we interpret such results with only 58% of respondants? I wouldn't go further in the study, but i'd like to know if some have already faced that problem, and how they delt with it. thanks in advance alain
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