I lost track of the original query, but someone was asking about a study by Freiman et al. I talk about this on my web pages at
http://www.childrens-mercy.org/stats/journal/mountain.asp I link to the NEJM article, but a better version appears as a chapter in a wonderful book: Medical Uses of Statistics Second Edition. John C. Bailar III, Frederick Mosteller (1992) Boston, Massachusetts: NEJM Books. My web page is currently undergoing major revisions, but I do discuss the Freiman study because it highlights (as have many other studies) the problem of inadequate sample sizes in most research studies. I'm trying to find some more recent studies that support the same conclusion, and I put a few tentative references on that page. But if anyone has a good reference that shows the problems with sample sizes, please let me know. Steve Simon, [EMAIL PROTECTED], Standard Disclaimer. The STATS web page has moved to http://www.childrens-mercy.org/stats. . . ================================================================= Instructions for joining and leaving this list, remarks about the problem of INAPPROPRIATE MESSAGES, and archives are available at: . http://jse.stat.ncsu.edu/ . =================================================================
