In article <[EMAIL PROTECTED]>,
 "jackson marshmallow" <[EMAIL PROTECTED]> wrote:


> 1) Two samples of are given and I need to compare their means and variances.
> The distribution of the population is unknown. Can I use the F-test and the
> t-test? Is it necessary that the sample _means_ have a Gaussian
> distribution? Is it sufficient? Maybe I misunderstand something here...

Both the t-test and F-test assume samples are from a normal (Gaussian) 
distribution.  The t-test is reasonably robust, i.e., the sample 
distribution needs to deviate quite a bit from normal before conclusions 
based on the t-test are likely to be invalid. But, the F-test is more 
senistive to deviations from normality and probably shouldn't be used if 
there is reason to suspect the sample distribution isn't normal.

> 2) I need to calculate the significance of correlation between two
> sequences. I would actually prefer to use randomization, but the sequences
> may be too short. Another option is to perform linear regression and
> calculate the significance of the slope using a t-test (?). When is it
> valid?

Linear regression (least squares) assumes a model of the form

y_n = m x_n + b  + e_n

where m and b are the desired regression parameters and e_n is the error 
associated with observation y_n. Further, it is assumed the e_n are from 
a normal distribution. 

It isn't clear to me whether this model is applicable to your problem 
with sequences.

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