The only issue on an Uno would be interrupt latency. If you disable all other interrupts, latency should be easily low enough. The only real advantage of going to ARM is interrupt priority. You could assign the sampling interrupt to maximum priority without having to disable other interrupts.

Les

On 21/01/2022 14:55, Ralph Stirling wrote:
I would suggest starting with a more capable microcontroller.  I like the $15 
Adafruit ItsyBitsy M4 modules, which are programmable with the Arduino IDE, but 
have a 120MHz clock, 32 bit timers, floating point hardware, and two 1Mhz 12bit 
adc's.  Their processor is an ATSAMD51 (Cortex M4).  The original Uno is very 
limited for precision timing.

-- Ralph



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