A genome packaged as "inscribed matter" is discussed only briefly in the paper linked below.
 
"There have been some speculations that a simple biological system carrying a message and capable of self-replication in suitable environments may be one possible channel for interstellar communication (Yokoo and Oshima, 1979, and Nakamura, 1986). These kinds of ideas have several and severe objections. For example, the impossibility of predicting the environment of the target star in order to favor the self-replication of the molecular structure, the impossibility of avoiding the destruction of the content of the message by molecular mutations, and the impossibility for us to distinguish between a "natural" organism and a real biological interstellar message."
 
If a "Common Europoid" hypothesis can be supported (and I think I have at least the outlines of a case), the "impossibility of predicting the environment" objection may not have quite as much force.  It'll still be impossible, of course, but hey, it's impossible to cross a busy street on a "walk" signal without risk of getting run over, but we still do it all the time because it works almost all the time.
 
The recent discovery of stable "junk DNA" would seem to knock down the mutation objection, unless by "molecular mutations" the author is referring to cosmic ray interference - a problem that interstellar shielding could solve -- or quantum positional uncertainties over long time scales causing the inscribed signal to 'rot', which I think is either ridiculously improbable, or solvable with an active transport that regenerates the message using error correcting codes.
 
The same "junk DNA" discovery - that you can erase all of the silent DNA from of a mouse sequence, and you still leave a recipe for a normal-seeming mouse - suggests that the problem of distinguishing between life evolved in the solar system and life prepared outside the system may not be so hard.  It reduces to something like the garden-variety SETI problem, once you've identified a candidate: how do you tell if that "stable junk DNA" is just noise, or something else, and if it's something else, is it intelligently fabricated?  I assume that, by now, someone has looked at genomic information currently on hand for obvious markers - like pi out to 200 bits or something like that.  (Even just "zero out to 200 bits" would be enough, right?  It just has to be obvious and highly improbable.)  So maybe genomic SETI is easily declared a dead-end.  But maybe it's subtler than that, and subtle for some reason we haven't figured out yet.  Maybe the very fact that there ARE stable junk sequences is a hint to us that they aren't junk.
 
It could be that I've been writing memory-efficient code for too many years of my programming career, but it seems to me that evolution would tend to optimize out useless bits, not evolve to preserve them.  "Intelligent Design" dogma may be the least of our problems - "Blind Watchmaker" is fine with me, until someone proves otherwise, but what are we to make of "Blind Rube Goldberg", i.e., of a nonsentient process that seems a little crazy and stupid, like a programmer who pads out his programs not just with commented-out code (quite understandable, if overdone in practice), but also with inline comments full of word salad?  I don't know enough about genetics to assert confidentlly that this is what the discovery of stable 'junk' DNA amounts to.  I wish I did know.  The only explanation I can think of is a hazy memory of a paper by a guy writing about energy and computation, in which he said that we should keep in mind that erasing bits costs energy too.  Collecting garbage isn't easy either.  It may be that efficient memory management is beside the point in evolution, given the vast amount of space to work with.
 
-michael turner
 
 
 
 
----- Original Message -----
Sent: Saturday, September 04, 2004 5:01 AM
Subject: Re: ET bits in "junk" DNA (was Re: A response to Rose and White's paper)

I think you will find this article interesting.  Scroll down to near the end before the bibliography:
 
 
Larry
 
 
----- Original Message -----
Sent: Friday, September 03, 2004 9:01 AM
Subject: ET bits in "junk" DNA (was Re: A response to Rose and White's paper)


> Michael:
>
> What do you think of Paul Davies' hypothesis in "Do we have to spell it
out"
> (New Scientist vol 183 issue 2459 - 07 August 2004, page 30 -- see excerpt
> below) that ET might have inserted a message into highly conserved
sequences
> of junk DNA? Note that further support for panspermia is provided in
"Alien
> microbes could survive crash-landing" (Nature online: 02 September 2004;
> doi:10.1038/news040830-10), although some form of cosmic ray/gamma ray
> protection would be required for extrasolar-system propagation.

I think Jack Reeve mentioned something about this earlier on the list.

I love this idea more than life itself (um, as it were.)  When people ask
me if I think aliens ever have visited, or will visit, I say, "Either never,
or long before we evolved."  Aliens could be all ready to bloom
(or metastasize, if you're the paranoid type) as soon as we decode them
from the global genome.  Or there may be just some interesting message
in the DNA bottle.

> Davies said:
>
> So might ET have inserted a message into the genomes of terrestrial
> organisms, perhaps by delivering carefully crafted viruses in tiny space
> probes to infect host cells with message-laden DNA? It's an idea that has
> been swirling around for a few years, and has recently been championed by
> the Apollo astronaut Rusty Schweickart. But on the face of it, there is a
> serious problem. Living cells are not completely immune to change.
Mutations
> introduce random errors into the stored information, and over a long
enough
> time span they would inexorably transform ET's message into molecular
> gobbledygook.

True enough I guess, and with a long enough transit time, maybe there's even
the danger of mutation from simple Heisenberg position uncertainty, even if
bugs
were adequately shielded from radiation somehow.  Though I wouldn't
know where to begin computing those probabilities.  Maybe they are
negligible after all.

> To minimise the effects of mutations, it would make sense to incorporate
the
> message into a highly conserved segment of DNA. Such segments are normally
> associated with key coding regions of the genome that control the most
vital
> functions of the organism. They tend to be unchanged between species,
> suggesting an ancient origin. Mutations in such regions are invariably
> fatal. But unfortunately tinkering with them by inserting alien DNA would
> likely prove as lethal as any random mutation.

Yes, from *mutations*. But there may be more than one way to rearrange
features
stably across generations to the same effect - an arrangement might convey
bits somehow, if there are enough degrees of freedom.  Think of a computer
program that can be written a number of ways.  A mutation is like
changing one character randomly, and if that's not changing meaningless
whitespace to other meaningless whitespace, the program's gonna crash,
or do weird things (or not even compile).  However, if you swap two lines
that have no execution-order dependencies, you're OK.  Could you
steganographically encode a message in a program by drawing from
the space of possible behavior-preserving transforms of the source code?
I'm sure you can. Can you do this with DNA as well?  I'm not so sure
about that.  But ... read on ... it might be irrelevant.

> Conversely "junk" DNA - sections of the genome that seem to serve no
useful
> purpose - can be loaded with all manner of genetic oddments without
> affecting the performance of the cells. Inserting a message here would
> almost certainly be harmless. The trouble is, junk DNA is famous for
> accumulating lots of mutations. So the choice seems to be between killing
> the messenger and compromising the message. What is needed is a region of
> junk DNA that is also highly conserved.
>
> Until recently, this would have been regarded as an oxymoron. But no more.
> Genomics researchers at the Lawrence Berkeley National Laboratory in
> California who compared human and mouse DNA have reported the discovery of
> vast, highly conserved sequences of junk DNA (New Scientist, 5 June, p
18).
> These segments are apparently surplus to requirements. When the
researchers
> deleted them from the mouse DNA, the animals seemed to be perfectly
normal.
> If ET has put a message into terrestrial organisms, this is surely where
to
> look.

And think of the money saved on giant radiotelescope arrays.

In any case, for natural panspermia, I think we're talking about a
scenario in which some object crosses interstellar space relatively
slowly, with adequate shielding, maybe aerobrakes and gravity-
brakes across a lucky sequence of gas-giants to reduce the
kinetic energy gathered from plunging toward the sun, and
finally makes it through the atmosphere to Earth.  (Or Europa!
Back on topic!  Finally!)  That last part doesn't strike me as unlikely
at all.  The right kind of rock can plop down in an ocean without
even getting very warm inside from passage through the
atmosphere.  That part's proven. The earlier parts of the journey
are what bother me - I think to make panspermia LIKELY,
not just POSSIBLE, you've got to have intelligent engineering
behind it.  But if someone can put reasonable numbers
in front of me suggesting otherwise, I'm all ears.  Or eyes.

Speaking of "vast, highly conserved sequences of junk,"
I haven't cleaned my room for over a month.  So this should be
my last posting on this thread for, oh, at least 24 hours.
OK, make that 12 hours.  Less than a million years, anyway.

-michael turner
[EMAIL PROTECTED]



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