Surely diy bioers are working on safe locks. Think of Cathal's idea of the
colV cluster instead of antibiotics. Or trying to utilize auxotrophic
strains.
Am 13.01.2015 16:01 schrieb "Julian Chollet" <[email protected]>:

> But hey,  you have 10 years to prove SCENIHR wrong! Go ahead and surprise
> the world!
>
>
> that’s a really nice challenge for DIYbio… forget the low hanging fruits!!
> Who is in??
>
> Thank you for the elaborate explanations, Markus!!
>
>
> Am 13.01.2015 um 13:20 schrieb Markus Schmidt <[email protected]>:
>
> Dear Julian, Aandreas et al.
>
> I will try to clarify clarify these points:
>
> @Andreas:
> Though " a submission will not be considered if it is: -> is related to
> policy or risk management aspects, which is outside the scope of Scientific
> Committees’ activities." So what do they want?
>
> The wording might be a bit confusing for someone not workin in the field
> of risk assessment/management, but the terms risk assessment and risk
> management describe different procedures. Risk assessment is more narrow as
> it only deals with the identification, and evalaution (e.g. Probability,
> hazard) of a risk, while risk management also deals with how organizations,
> governments etc deal and manage those risks. Management always includes
> values and priorities and are thus more political, while the assessment is
> more of a pure science activitiy (taken with a grain of salt).
>
> For more details on the distinction between Risk assessment
> and Risk Managemet see e.g. :
> http://en.wikipedia.org/wiki/Risk_assessment
> http://en.wikipedia.org/wiki/Risk_management
>
> @ Julian
> Part of the title: “Risk assessment methodologies and safety aspects”
> Page 13 and 42:
> “Outside the scope of the current mandate are the social, governance,
> ethical, and security implications of SynBio.”
> Page 42:
> “Question 4: What are the implications for human and non-human animal
> health and the environment of likely developments in SynBio […]”
> —> please explain the difference between “safety aspects” and “security
> implications”
> —> if we should not give feedback “related to policy or risk management
> aspects”, what else do you want?
>
> According to the WHO (World Health Organization. 2004. Laboratory
> Biosafety Manual, Third Edition, Geneva.) biosafety is the prevention of 
> unintentional
> exposure to pathogens and toxins, or their accidental release, whereas
> biosecurity is the prevention of loss, theft, misuse, diversion or intentional
> release of pathogens and toxins. So bioERROR vs. bioTerror.
>  While the effects of both safety and security could be similar, the
> assessment (and furhter down the line also the counter-meassures) are
> different.
>
> Please note that the Opinion answers a set of questions that where given
> to SCENIHR by the EC (
> http://ec.europa.eu/health/scientific_committees/docs/synthetic_biology_mandate_en.pdf)
> and in that mandate the questions only deal with risk assessment and and
> safety, not security. This doesn’t mean that security or risk management
> are not important , it means that SCENIHR is seen as the right group to
> science based answers to these questions.
>
>
> Page 43:
> “the probability of unintentional harm might increase because DIYbio is
> more popular.”
> —> DIYbio is more popular than conventional research!!?! Yeaa! That’s good
> news!! ;)
> The comparator „Conventional research“ is not in the original text but was
> introduced by you. What is meant is that DIYBio more popular than before,
> like in the old days of genetic engineering.
>
> Page 46:
> “Contributions to built-in safety locks from the DIY (molecular)
> biologists community are not expected, because the development of these
> locks are beyond the current capabilities of this community”
> —> really? not even in 10 years?
> “The SCs have confined the scope of its analysis to the foreseeable future
> (up to 10 years), acknowledging that its findings should be reviewed and
> updated again in another decade.”
>
> Yes, not expected. Based on what is going on now there is hardly any
> indication that this will come from the DIYBIo community. But hey,  you
> have 10 years to prove SCENIHR wrong! Go ahead and surprise the world!
> ;-)
> MINORITY OPINION
> None
> —>21 People were working on one opinion in such a controversial field and
> you really reached a consensus???
> In fact even more people were involved because SCENIHR (the 20 people) is
> only one of 3 comittees that need to agree on the text, the SCENIHR wrote
> the text but also the other two had to agree: SCHER and SCCS (
> http://ec.europa.eu/health/scientific_committees/emerging/requests/index_en.htm
> )
>
> This is not necessarily surprising, the groups spent a lot of time
> debating the issues and in this case a minority opinion was not formulated.
> The risk assessment and safety opinioon is the second of 3 opinions. In the
> first one on defintion (
> http://ec.europa.eu/health/scientific_committees/consultations/public_consultations/scenihr_consultation_21_en.htm)
>  we did had a minority opinion in the draft opinion (that was also open to
> public consultation). But for the final opinion the scientific commitee was
> able to reach consensus.
>
>
>   Best wishes, Markus
>
>
>
> Am 13.01.2015 um 10:39 schrieb Julian Chollet <[email protected]>:
>
> @Luc: EPFL rocks!!   ;)
> <Science Editorial 09.01.2015 - Judging synthetic biology risks .pdf>
>
>
> Am 13.01.2015 um 10:12 schrieb Luc Henry <[email protected]>:
>
> Cathal: My ex-institution cancelled its subscription to Science.
>
> Very interesting move..
>
> Here's the press release:
>
> 05/12/2014 - Further to new unacceptable contractual conditions, the EPFL
> decided not to renew its subscription to Science Online. Hence online
> access could be cut from December 13, 2014 on. However, back files will
> remain accessible, as well as the printed issues.
>
> *THE RATIONAL BEHIND THE DECISION TO END ACCESS TO SCIENCE JOURNALS*
>
> Science AAAS publisher, is taking advantage of its dominant position and
> trying to impose not only an unjustified price increase, but also new
> contract terms, which are very restrictive and as a result unacceptable for
> us (more details on http://library2.epfl.ch/en/scienceonline)
>
> The EPFL has therefore decided not to renew its subscriptions under the
> present conditions.
>
> On 13 January 2015 at 09:33, Andreas Stuermer <[email protected]>
> wrote:
>
>> Haven't had any time yet to read them. Though " a submission will not be
>> considered if it is: -> is related to policy or risk management aspects,
>> which is outside the scope of Scientific Committees’ activities." So what
>> do they want?
>>
>> Gotta dig into it, because it directly affects me though.
>>
>> On Tue, Jan 13, 2015 at 12:10 AM, Cathal (Phone) <
>> [email protected]> wrote:
>>
>>> Anyone have a pdf of that Science ed?
>>>
>>>
>>> On 12 January 2015 22:45:13 GMT+00:00, Markus Schmidt <
>>> [email protected]> wrote:
>>>>
>>>> Dear all.
>>>>
>>>> Following the Science Editorial (
>>>> http://www.sciencemag.org/content/347/6218/107.summary) about the EC
>>>> opinion on synbio and safety, the Guardian has picked up the topic in its
>>>> recent podcast also discussing DIYBio.
>>>>
>>>> http://www.theguardian.com/science/audio/2015/jan/12/risks-diy-synthetic-biology-safety
>>>>
>>>> The heart of the matter, the SCENIHR EC opinion on synbio, biosafety
>>>> and risk assessment includes a proper section on DIYBio and is currently
>>>> open for public consultation if you feel like commenting
>>>>
>>>> http://ec.europa.eu/health/scientific_committees/consultations/public_consultations/scenihr_consultation_26_en.htm
>>>>
>>>> Since these EC opinions are known to carry some weight/be influential
>>>> in different types of policy and agenda setting, I can easily imagine the
>>>> EC and the authors of the opinion (I am one of them) to be happy to get
>>>> some sincere feedback from the DIYBio community! Deadline for feedback is 
>>>> *3
>>>> February 2015**.*
>>>>
>>>> Best regards, Markus
>>>>
>>>>
>>>>
>>> --
>>> Sent from my Android device with K-9 Mail. Please excuse my brevity.
>>>
>>
>>
>>
>> --
>> ---------------
>>
>> http://diyspartanbiotech.files.wordpress.com/2014/03/genetic-engineering-and-synbio-for-beginners-v1.pdf
>>
>
>
>
>
>

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