On Monday, July 22, 2019 at 8:39:57 PM UTC-5, Dan Sonik wrote:
>
> Hello List, 
>
> In my extracurricular studies, I have been reading Kolb's "An Introduction 
> to Brain and Behavior" (2e, 2005), specifically the opening chapter on the 
> origins of the feedback loop between brain and behavior, and the dramatic 
> impact that small lesions throughout the brain have on ones behavior.  
>
> This is relevant to a number of discussions on this list (to my 
> mind/brain) as it seems to create some rather severe constraints 
> surrounding the success criteria of a "duplication" of a brain. 
>
> From the reading, it would appear that, in order to a proper digital 
> duplication of a brain to take place, the so-called "substitution level" at 
> which you would be willing to say "Yes doctor" would actually have to be 
> satisfied at multiple levels of analysis (i.e. chemically, neurochemically, 
> biologically, physically, socially, psychologically, interpersonally). 
> These levels of analysis are not captured in any complete mathematical 
> formalism that I know of. 
>
> A doctor intending to "duplicate your brain" would have to plan on a) 
> copying your brain in a current state (statically + dynamic equations to 
> fill in details of "next state" operation; b) destroying some or all parts 
> of your brain to be replaced/duplicated; c) reconstituting your brain (in 
> either the biological way (probably absolutely intractable) or some 
> sufficiently digitally exact copy (today, practically intractable) such 
> that it replicated the function of what was to be replaced/duplicated. This 
> would have to be perfect enough to keep all of the levels of 
> substitution/analysis described above in tact. 
>
> We know from even seemingly minor cases of brain damage that the "person" 
> before the damage (i.e. YOU) and the "person" after the damage (YOU?) are 
> not the same... memories are fragmented, behavioral patterns change, and 
> significant others who would previously have enjoyed YOUR company might now 
> be frustrated when spending time with YOU.  
>
> So would you ever say yes to the doctor? Why? What kind of confidence 
> would you need to be willing to bet such a duplication/replacement would be 
> successful? 
>
> I submit that your confidence would (and should) be quite low. This is 
> because a) there could be more than one substitution level; b) dynamical 
> properties of the brain are just as important (if not more) as their 
> general static properties (eg. the connectome); c) intersubjective 
> agreement about whether  you are the same person is just as (if not more) 
> important after duplication, as it is assumed after the duplication that 
> you will go on to join society in whatever capacity you did before the 
> duplication. 
>
> My computer earlier today wouldn't boot up. Apparently, one of the key 
> files it needed got corrupted and I needed to replace it using a restore 
> disk. It took about an hour to fix. This is for an actual full fledged 
> honest-to-goodness digital machine. And its failure was completely 
> unpredictable based on previous behavior of the machine.Either a) I did 
> something in my previous session to cause the corruption or b) the 
> corruption happened randomly.  
>
> What about something as complex (and integrated into its environment) as 
> the brain? What could go wrong in a duplication here? 
>
> TL;DR CONCLUSIONS -- 
>
> 1) Thought experiments about the completion of duplications/destructions 
> of brains gloss over so many necessary empirical details regarding brain 
> function and continual identity that they can come to no useful conclusions 
> about anything.  
>
> 2) "Mechanism" as used on this list (i.e. the computational hypothesis 
> that our minds can (and indeed are) replicated in the structure of the 
> natural numbers is FALSE. 
>



Any brain (or part-brain) replacement would have to be made (biocompiled) 
via synthetic biology, with possibly some new neural-like polymers w/ 
neurochemistry as in the brain. 

@philipthrift

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