*It has long been a mystery about what the mechanism that forms Long
term memories is, but in the March 27, 2024 issue of the journal Nature
there is an article that takes a big step towards explaining it. I found it
interesting because memories are a large part of what defines us. It turns
out there is a relationship between the immune system remembering a virus
or bacteria it had encountered before and mental memories. When long-term
memories are formed there is a surge in electrical activity that is so
powerful it snaps a cell's DNA, and the resulting DNA fragments triggers an
immune response to repair the damage and cement the memory. It's strange
that during the damage-and-repair cycle a brain cell encodes long term
memories using a mechanism similar to the way the immune system remembers
previous microorganism invaders, it's just that the inflammation is caused
by broken strands of a cell's own DNA and not bacterial or viral DNA. They
also found the protein responsible for this memory inducing inflammation,
it's called TLR9, when they deactivated the gene that produces TLR9 mice
found it very difficult to form long-term memories.*

*Innate immunity in neurons makes memories persist*
<https://www.nature.com/articles/d41586-024-00679-4>


John K Clark    See what's on my new list at  Extropolis
<https://groups.google.com/g/extropolis>
mtl

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