*Yesterday the journal nature published the following article, I think it's
an important step towards Drexler style Nanotechnology .*


*‘ChatGPT for CRISPR’ creates new gene-editing tools
<https://www.nature.com/articles/d41586-024-01243-w?utm_source=Live+Audience&utm_campaign=cd02bd946d-nature-briefing-daily-20240430&utm_medium=email&utm_term=0_b27a691814-cd02bd946d-50169436>*
*I found these quotes to be especially interesting:*

*“It’s really just scratching the surface. It’s showing that it’s possible
to design these complex systems with machine-learning models, the first
successful editing of the human genome by proteins designed entirely with
machine learning"says Ali Madani, a machine-learning scientist and chief
executive of the biotechnology firm Profluent. Because CRISPR gene-editing
systems comprise not only proteins, but also RNA molecules that specify
their target, Madani’s team developed another AI model to design these
guide RNAs"*

*"The most promising Cas9 protein — a molecule they’ve named OpenCRISPR-1 —
was just as efficient at cutting targeted DNA sequences as a widely used
bacterial CRISPR–Cas9 enzyme, and it made far fewer cuts in the wrong
place. The researchers also used the OpenCRISPR-1 design to create a base
editor — a precision gene-editing tool that changes individual DNA
‘letters’ — and found that it, too, was as efficient as other base-editing
systems, as well as less prone to errors."*

 See what's on my new list at  Extropolis
<https://groups.google.com/g/extropolis>

l8c

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