*Chinese researchers report in the January 15 2025 issue of the journal
Cell Metabolism that mice aged between 20 and 25 months, equivalent to
humans aged between 60 and 70 years, that were injected with something
called "miR-302b", lived on average 4.5 months longer than the control
group of mice that were just given injections of saline. Also, compared
with the control group, they regrew more hair, maintained a higher body
weight, could stay balanced on a rotating rod for longer, had better grip
strength for their weight, could go through a water-maze test faster,
maintain their mental abilities better and had fewer inflammatory proteins
in their blood.*

*The lead author, Guangju Ji, said: *

 *“These results collectively demonstrate that miR-302b treatment not only
extended the lifespan of mice but also significantly improved their
physical and cognitive functions while reducing markers of ageing,”*

*They also found that in vitro human embryonic stems cells exposed to
miR-302b "reversed senescence by restoring their proliferative
capacity";  **miR-302b
is a very small non-coding RNA fragment that regulates gene expression and
had previously been known to be somehow involved in the process of
suppressing cancer cells. Apparently it is involved in more than just that.*


*Exosomal miR-302b rejuvenates aging mice by reversing the proliferative
arrest of senescent cells*
<https://www.sciencedirect.com/science/article/pii/S1550413124004819?ref=pdf_download&fr=RR-2&rr=90576104fdc2e9f3>

*John K Clark    See what's on my new list at  Extropolis
<https://groups.google.com/g/extropolis>*
7qm

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