On Monday 06 October 2008 15:46:00 [EMAIL PROTECTED] wrote:
> New to Exim and using Exim 4.43 and Dovecot 1.0.13 on CentOS 4.6. Server
> sends and receives mail but when sending from Squirrelmail it is sent as
> user '[EMAIL PROTECTED]' and because of this replies are rejected with a
> '550 relay not permitted (in reply to RCPT TO command)'
> Any ides on this one? Used to work normally with Postfix in place of Exim
> on same server.
>
> regards,
> Chas.

See the 
php_value mail.force_extra_parameters
option for your apache configuration.

Of course, you could also create an alias apache to prevent the 550's.

Greets,

        Oliver Heesakkers

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