> 
> If Exim tries to deliver a message to a remote server and gets a 5xx
> code back, say 550 no such user, am I right in thinking the message
> should fail right away with an NDR, not remain on the queue being
> re-tried?

Yes. The remore system has sent a permanent rejection response back, the email 
should be regarded as unable to be delivered.
> 
> More sticky, if a remote server refuses connections from Exim - say it
> is firewalling off the connecting ip, should that fail at once or stay
> on the queue for x hours?

Exim should queue mail for the remote server - based on the retry time rules 
defined. 

 John


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