http://www.latimes.com/news/nationworld/nation/la-sci-
schaivodeath23mar23,0,3402521.story?coll=la-home-headlines


Ceasing Food and Fluid Can Be Painless


Concerns for Schiavo's comfort have galvanized the debate. But experts say 
dying of 
starvation and dehydration is a peaceful end for the ill.
By Karen Kaplan and Rosie Mestel
Times Staff Writers

March 23, 2005

After suffering through cancer, the middle-age woman decided her illness was 
too much 
to bear. Everything she ate, she painfully vomited back up. The prospect of 
surgery and a 
colostomy bag held no appeal.

And so, against the advice of her doctors, the patient decided to stop eating 
and drinking.

Over the next 40 days in 1993, Dr. Robert Sullivan of Duke University Medical 
Center 
observed her gradual decline, providing one of the most detailed clinical 
accounts of 
starvation and dehydration.

Instead of feeling pain, the patient experienced the characteristic sense of 
euphoria that 
accompanies a complete lack of food and water. She was cogent for weeks, 
chatting with 
her caregivers in the nursing home and writing letters to family and friends. 
As her organs 
finally failed, she slipped painlessly into a coma and died.

In the evolving saga of Terri Schiavo, the prospect of the 41-year-old Florida 
woman 
suffering a slow and painful death from starvation has been a galvanizing force.

But medical experts say going without food and water in the last days and weeks 
of life is 
as natural as death itself. The body is equipped with its own resources to 
adjust to death, 
they say.

In fact, eating and drinking during severe illness can be painful because of 
the demands it 
places on weakened organs.

"What my patients have told me over the last 25 years is that when they stop 
eating and 
drinking, there's nothing unpleasant about it -- in fact it can be quite 
blissful and 
euphoric," said Dr. Perry G. Fine, vice president of medical affairs at the 
National Hospice 
and Palliative Care Organization in Arlington, Va. "It's a very smooth, 
graceful and elegant 
way to go."

Schiavo, who hasn't had any food or water since Friday, has been in a 
persistent vegetative 
state for 15 years that makes it impossible for her brain to recognize pain, 
doctors say.

"Her reflexes with respect to thirst or hunger are as broken as her ability to 
think thoughts 
or dream dreams or do anything a normal, healthy brain does," Fine said.

But even if her brain were functioning normally and she were aware of her 
condition, she 
would be comfortable, doctors say.

"The word `starve' is so emotionally loaded," Fine said. "People equate that 
with the 
hunger pains they feel or the thirst they feel after a long, hot day of hiking. 
To jump from 
that to a person who has an end-stage illness is a gigantic leap."

Contrary to the visceral fears of humans, death by starvation is the norm in 
nature -- and 
the body is prepared for it.

"The cessation of eating and drinking is the dominant way that mammals die," 
said Dr. Ira 
Byock, director of palliative medicine at Dartmouth Hitchcock Medical Center in 
New 
Hampshire. "It is a very gentle way that nature has provided for animals to 
leave this life."

In a 2003 study published in the New England Journal of Medicine, 102 hospice 
nurses 
caring for terminally ill patients who refused food and drink described their 
patients' final 
days as peaceful, with less pain and suffering than those who had elected to 
die through 
physician-assisted suicide.

The average rating given by the nurses for the patients' quality of death was 
an 8 on a 
scale where 9 represented a "very good death" and 0 was a "very bad death."

Patients deprived of food and water will die of dehydration rather than 
starvation, unless 
they succumb to their underlying illness first.

Without fluids, the body loses its ability to maintain the proper balance of 
potassium, 
sodium, calcium and other electrolytes in the bloodstream and inside cells.

The kidneys react to the fluid shortage by conserving as many bodily liquids as 
possible.

The brain, which relies on chemical signals to function properly, begins to 
deteriorate. So 
do the heart and other muscles, causing patients to feel tired and lethargic.

"Everything in the body is geared toward trying to maintain that normal 
balance," Fine 
said. "The body will do everything it can to maintain this balance if it's 
working well."

Meanwhile, the body begins mining its stores of fat and muscle to get the 
carbohydrates 
and proteins it needs to make energy.

"If you mine too many proteins in the heart, it gets unstable," Sullivan said. 
That can give 
rise to an irregular heartbeat, which can cause the patient to die of cardiac 
arrest. Or, if 
the muscles in the chest wall become weak, the patient can end up with 
pneumonia, he 
said.

Patients already weakened by disease begin feeling the impact after a few days, 
Fine said.

They eventually descend into a coma and finally death. The entire process 
usually takes 
one to two weeks, although a patient who is otherwise healthy -- such as 
Schiavo -- could 
hold on much longer.

Throughout the process, the body strives to suppress the normal feelings of 
pain 
associated with deprivation.

That pain of hunger is only felt by those who subsist on small amounts of food 
and water 
-- victims of famine, for instance, or concentration-camp inmates. They become 
ravenous 
as their bodies crave more fuel, said Sullivan, a senior fellow at Duke's 
Center for the 
Study of Aging.

After 24 hours without any food, "the body goes into a different mode and 
you're not 
hungry anymore," he said. "Total starvation is not painful or uncomfortable at 
all. When we 
were hunting rabbits millions of years ago, we had to have a back-up mode 
because we 
didn't always get a rabbit. You can't go hunting if you're hungry."

After a few days without food, chemicals known as ketones build up in the 
blood. These 
chemicals cause a mild euphoria that serves as a natural anesthetic.

The weakening brain releases a surge of feel-good hormones called endorphins.

Doctors also have a host of treatments to ameliorate acute problems, such as 
sprays and 
swabs to moisten dry mouths and creams to moisturize flaky skin. They can also 
administer morphine or other powerful painkillers.

Sullivan said doctors are likely to give some to Schiavo, although, "frankly, I 
think they 
might as well give it to each other, because it will probably be more painful 
for them than 
it will be for her."
Copyright 2005 Los Angeles Times






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