The antioxidant myth is too easy to swallow
People are hooked on the fallacy that 'antioxidant' is a byword for
'healthy' – perhaps because the truth is less appealing
  [Blueberries] 'Blueberries best be eaten because they taste good, not
because their consumption will lead to less cancer.'
When the press release arrived in our inboxes, we knew what would happen
next. A controversial Nobel laureate had stated, in a peer-reviewed
paper
<http://rsob.royalsocietypublishing.org/lookup/doi/10.1098/rsob.120144> 
he described as "among my most important work", that antioxidant
supplements "may have caused more cancers than they have prevented".

Even the most fad-friendly sections of the UK media
<http://www.dailymail.co.uk/health/article-2259280/Superfoods-make-cance\
r-MORE-likely-says-pioneer-DNA-study.html>  were bound to cover the
story.

In reality, Professor James Watson – one of the DNA double-helix's
founding fathers – was only restating what we at Cancer Research UK
(along with many others) have been pointing out for years. Large studies
have repeatedly shown that, with the possible exception of vitamin D
<http://www.ncbi.nlm.nih.gov/pubmed/17556697> , antioxidant supplements
have negligible positive effect on healthy people, at least in terms of
important things such as preventing people getting cancer or dying
prematurely. And some supplements – notably vitamins A, E and
beta-carotene – even seem to slightly raise the risk of disease and
early death.

It's a topic we at Cancer Research UK come back to
<http://scienceblog.cancerresearchuk.org/2009/06/25/what-are-antioxidant\
s-and-are-they-good-for-us-part-2/>  again and again
<http://scienceblog.cancerresearchuk.org/2012/12/07/alternative-cancer-t\
reatment-claims-in-the-media-are-damaging-and-misleading/>  on our
science blog and on our social media pages. But as a quick trawl of
Twitter reveals <https://twitter.com/search/antioxidants> , huge swaths
of the public remain convinced that "antioxidant" is a byword for
"healthy".

This isn't going to be a Goldacresque run-down of study after study of
evidence (although here's a handy Cochrane review
<http://summaries.cochrane.org/CD007176/antioxidant-supplements-for-prev\
ention-of-mortality-in-healthy-participants-and-patients-with-various-di\
seases>  for the nerds). What's so interesting about the antioxidant
myth is its wider cultural and social dimension. Why is this perception
so hard to shift? And is there anything we can do about it?

One possible reason for our entrenched attitudes is the ubiquitous use
of the word "antioxidants" in adverts proclaiming the health benefits of
various foods and drinks. This isn't for want of regulation, and the
Advertising Standards Authority have repeatedly upheld complaints
<http://www.asa.org.uk/Rulings/Adjudications.aspx?SearchTerms=antioxidan\
ts>  about adverts that make unsupported claims about antioxidants'
benefits.

But the much weaker claim that a product merely "contains high levels of
antioxidants" leaves health claims implicit, and keeps regulators at
bay. A brand of "super-broccoli" – launched with much fanfare in
late 2011
<http://scienceblog.cancerresearchuk.org/2011/10/06/super-broccoli-no-fi\
rm-evidence-it-prevents-cancer-in-humans/>  – was bred to contain
high levels of a chemical that ultimately, according to the product's
website, "boosts our body's Antioxidant Enzyme levels". So good it's
Capitalised.

So the relentless drip drip of health product advertising –
particularly against a background of continual reports of Britain's
ill-health, and our supposedly irresponsible behaviour – makes our
trenchant hold on the antioxidants myth all the more understandable. We
need this stuff, we're told.

But there's probably a deeper reason for our collective refusal to
swallow the bitter pill of scientific evidence. The actual, proven
things that can reduce our risks of cancer, heart disease, diabetes
– and all the other chronic nasties that come with an ageing
population – are somewhat more prosaic. Don't smoke. Stay in shape.
Eat a balanced diet. Limit alcohol intake. Keep active. This is hard
work.

And as the resolution-filled new year kicks in, the exciting prospect of
a healthier life is replaced by the realisation that being healthy is a
long-term project. Popping a pill instead of going to the gym is a
tempting prospect for many of us. Confirmation bias is a powerful thing.

But the UK population is ageing, and likely to place a greater burden on
the NHS in future. We owe it to ourselves, and those will be paying for
our care, to make sure we're as healthy as possible for as long as
possible. Putting our faith in a word, and a pill – however
comforting it may sound – to do this for us is a mirage and a
fallacy. Antioxidants do not prolong our lives nor prevent cancer,
despite what we want to believe. As Professor Watson remarked in his
paper, "Blueberries best be eaten because they taste good, not because
their consumption will lead to less cancer."




http://www.guardian.co.uk/commentisfree/2013/jan/10/antioxidant-myth-eas\
y-to-swallow

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