Celiac disease: When gluten is broken up into fragments in the gut, those fragments induce the release of zonulin, which tells the tight junctions to become more permeable http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458511/. This happens to everyone whose guts come into contact with those gluten fragments, but the effect is enhanced in people with celiac. Their gluten-induced leaky gut is way more leaky than it should be, and it stays leaky long after the gluten has been gone. In fact, a common test for celiac http://www.ncbi.nlm.nih.gov/pubmed/10902869 is the very same intestinal permeability assessment I just mentioned. Read more: http://www.marksdailyapple.com/leaky-gut/#ixzz314Gv7AmP http://www.marksdailyapple.com/leaky-gut/#ixzz314Gv7AmP