Love this info!

Diagnosis

Diagnosis of T foetus infection is usually quite
straightforward. The organism exists in the intestine
as small, motile trophozoites, and these can be
detected under the microscope. For optimum results,
fresh faeces should be examined, and if any mucus has
been passed with the faeces this is the most likely
place to find the organisms.

Two other diagnostic tests are available which are
both more sensitive and specific for this organism.
Firstly, the organism can be cultured from faecal
samples using a system developed for diagnosis in
cattle. The ‘In Pouch tm TF' test (BioMed Diagnostics,
Oregon , USA ) uses a liquid culture system in a
sterile plastic pouch.

The other test that can be used is PCR (polymerase
chain reaction) – a sophisticated test that can detect
the presence of the genetic material of the organism.

Entire article found here: (A good reference, IMO)

http://www.fabcats.org/tritrichomonas.html

Lora





--- [EMAIL PROTECTED] wrote:

Here's the info my vet gave to me when we discovered
we had it here:

Trichomonosis in cats

According to Dr S. Marks of UC-Davis School of
Veterinary Medicine:  "Tritrichomonas foetus, the
primary causative agent of bovine trichomoniasis, has
recently been recognized as a protozoal [intestinal]
pathogen in cats."  One study showed a
high prevalence in cat show and cattery animals. 

Often misdiagnosed as Giardia, T. foetus infected cats
treated with an appropriate Giardia therapy do not
respond.

Clinical signs of Tritrichomonas foetus include
chronic or re-occurring diarrhea. Often "the anus is
red, swollen, and painful, and fecal incontinence is
not uncommon. Most cats are usually bright, alert, and
responsive, and in good body condition with a normal
appetite."

T. foetus can be found in cats not showing clinical
signs.

InPouchTF (Biomed Diagnostics, White City, Oregon)is a
test developed to identify Tritrichomonas foetus in
cows, but can be used in a veterinary hospital setting
to test cats for the protozoa.

This is the test we used to confirm Pharaoh's
diagnosis.  InPouch TF has shown a 90% rate of
sensitivity to the protozoa, a six-fold increase over
trying to diagnosis this protozoa via a
microscopic examination of fecal material.

Tritrichomonas foetus is not considered to be zoonotic
(transmissible to people) but as it can affect cows
and pigs, anyone with these animals and a cat with
chronic diarrhea has cause for concern.

At the time Dr. Marks wrote his presentation, no
treatment options were available. By June of this
summer (2005), after many drug trials had been
unsuccessful, Ronidazole was showing promise in
research trials.

Once diagnosed with Tritrichomonas foetus, Ronidazole
is the drug currently being tested for use in cats.
This is an 'off-label' use of the drug and is not
guaranteed to be a treatment.  Dosing being used by
researchers is 30-50mg/kg orally once every 12 hours
for 14 days. However, research has not yet decided if
this is the optimal dose.

Ronidazole is produced by SIGMA Pharmaceuticals. It
must be kept frozen. Currently it is a relatively
reasonably priced drug - this may change in the
future.

It is important to know that recovered cats can remain
infected. Periods of stress do seem to play a strong
role in recurrence of clinical signs.

The most sensitive test for Tritrichomonas foetus is a
PCR of DNA extracted from feces with a 97%+
sensitivity to the protozoa. This test is only
performed at the veterinary laboratory at North
Carolina State University. A lima bean sized amount of
feces must be placed in 5-10ml of rubbing alcohol for
proper stabilization of the sample in preparation for
testing.  

Sources

"Update of Feline Gastrointestinal Neoplasia,"  S.
L. Marks, BVSc., PhD, Diplomate ACVIM (Internal
Medicine, Oncology), Diplomate ACVN, lecture notes,
North American Veterinary Conference Postgraduate
Institute 2005 - Advances in Feline Medicine, Orlando
FL.

Personal notes, P. J. Yankauskas, VMD, Hyde Park VT

Personal consultation, P. J. Yankauskas, VMD, Hyde
Park VT

Their phone number, if you need to call for more info
is 802-888-7911, and you can tell them that Jennifer
O'Guin referred you to them about Trich diagnosis and
treatments. Thye should be able to
give you (or your vet) all the needed info.

Jenn
http://ucat.us
http://ucat.us/domesticcatlinks.html
Adopt a cat from UCAT rescue:
http://ucat.us/adopt.html  
Adopt a FIV+ cat: 
http://ucat.us/AWrescue/FIV/
Adopt a FELV+ cat:
http://ucat.us/FELVadopt.html

"Saving one animal won't make a difference in the
world, but it will make a world of difference for that
one animal."

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
I collect KMR kitten formula labels for Bazil, a 3 yr
old special needs cat who must live on a liquid diet
for the rest of his life.

Bazil's caretaker collects labels and sends them to
KMR, where they add up until she earns a free can of
formula!

PLEASE save your KMR kitten formula labels for Bazil!

If you use KMR, even just one can, please email me
for the NEW address to send them to!


        
                
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