This is the kind letter I got from Dr. Gfeller and he said it was
alright to post, He has the release date on the bottom,
Kelly
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Date: Tue, 5 Sep 2006 12:58:57 -0700 (PDT)
From: Roger W Gfeller <[EMAIL PROTECTED]>
Reply-To: Roger W Gfeller <[EMAIL PROTECTED]>
Subject: SAMe for cats
To: [EMAIL PROTECTED]
X-Antivirus: AVG for E-mail 7.1.405 [268.11.7/437]
Ms. Lane,
I thank you for your interest in my "theory" that SAMe may help
lessen the anemia seen in many chronically ill or severely injured cats.
Here's how I look at this. This has not been confirmed in a lab
study. Here's what we know: the cat has hemoglobin that is very
susceptible to oxidative injury. Oxidative injury is seen with
chronic or severe illness or injury. When the hemoglobin is damaged
by oxidative injury, the red cell is destroyed and the cat becomes anemic.
Normally, a cat will "protect" the hemoglobin using natural body
defenses such as glutathione. In the population of cats that I am
speaking of, the glutathione stores are quickly depleted for many
reasons and it is not repleted - usually because they are not
eating. SAMe provides a precursor to glutathione. Analysis of these
considerations makes me wonder - if we provide a glutathione
precursor such as SAMe, can we ameliorate the anemia? Is it as
simple as controlling the damage of oxidative injury? Or is it more complex?
Likley, it is a very complex problem, but I wonder if we could at
least lessen this problem by using something simple. It would take a
very concerted effort to gather the information and put it all
together to make a vaild scientific conclusion. I hope that in the
future, we, as a teaching center, will be able to take on projects
such as this.
Sincerely,
Roger W. Gfeller, DVM, DACVECC
President, Central CA Veterinary Specialty Center
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