Hi Jane,
I have used both feline interferon omega, (injectable, non FDA approved, expensive), and human interferon Alpha, (oral, easily obtained, inexpensive). As far as I know I was the first list member to procure a special FDA dispensation for the fio and I have to say, I was disappointed at the results. While I do believe that it helps with symptoms the great hope I had for it as a "cure" was dashed. I do suspect that it might be something that would help those cats first exposed to throw the virus, but at least anequdotally, it doesn't seem to help them reconvert once the virus has taken hold. If the darn stuff wasn't so expensive and hard to get I'd consider it a valuable tool in our arsenal, as things stand, I just don't know. IA on the other hand is something that I would always keep on hand and feel is worth using, (that is what I was suggesting the last time I brought up your using interferon for MeMe). It's easy to administer and it does seem to help most cats, at the very least, feel better.

I have never personally used Immuno-Regulin, but the reports from list members are enough to convince me that it is worth a shot, (no pun intended), when symptoms are not alleviated with more common treatments like antibiotics. There have been several accounts of it helping with symptoms of infection like fever spikes. From what I understand, it is a bacteria that when introduced causes a boost in immune response that also helps battle current unexplained symptoms. The recommended protocol is IV injection, but at least one of our list members had good results using it subq and Best Friends uses it IM on a monthly bases for their felv+ cats. Have you discussed using it with your vet? You might point her to the vets at Best Friends since you seem fortunate enough to have a vet that is willing to research options.

What type of antibiotic has MeMe been prescribed? There are so many different abx out there you may not have hit on the right one to help with her symptoms. Have you tried the broad spectrum abx like Baytril and/or Doxi? I am sending prayers and good thoughts that the recent lump you discovered has dissipated by now and that it was nothing more than a stubbornly swollen lymph node.
Hugs to both you and MeMe,
Nina

Jane Lyons wrote:
I am trying to decide what the best treatment would be for
my cat (MeMe) who has 'moderate, but improving symptoms' of FeLV.
(we are having success with stomatitis and giardia, but still have some
swollen glands and a runny nose).

I asked one vet that I use to order Virbagen Omega for me.
This is her response to my request:

Jane, The info on this is not encouraging. Besides the expense, the European vets don't feel it's a cure all. Here's a brief summary of the one study: J vet Int Med July-Aug 2004. "Therapeutic Effects of recombinant feline interferon-omega on felv-infected and felv/fiv infected symptomatic cats" Recombinant feline interferon omega or felv and felv/fiv cats compared to 42 controls, 39 Ifn treated cats at 9 ms, mortality was 39% in the Ifn cats, 59% in controls; at 1yr, mortality was 47% v.59%. Ifn treatment gave minor but consistent improvement in blood parameters (rbc count, wbc count).
So: statistical improvement but half still died by 1 year.   Dr.E

I have just read an article that was referenced on the Feline Leukemia site by Dr. Karen Thomas who was promoting the use of ImmunoRegulin. The article is not dated, and it is not clear if the information is current,
or if there is any connection to interferon.

Is there anyone who has experience with these treatments, or could direct me to someone who does?
Thanks very much

Jane







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