..interesting article on the web about pilling cats (which
is probably applicable to dogs as well), and the amount of time a pill can
stay in the esophagus (painful AND dangerous) if it is not followed by a
liquid chaser. Another site referred to a cat who had so many pills trapped
in her esophagus that it was completely blocked.



http://www.catinfo. org/pillingcats. htm



Here is the relevant part of the page, entitled "A Very Interesting Study:"





The following is a summary of a very interesting article that appeared in a
veterinary journal entitled Evaluation of the Passage of Tablets and
Capsules Through the Esophagus of the Cat. It is from a paper presented at
the 2001 American College of Veterinary Internal Medicine Forum. (They do
note at the end of the paper that the principles outlined also make good
sense for dogs.) This paper was submitted to one of the lesser-read journals
so a lot of veterinarians may not have seen it. This is extremely
unfortunate for all cats and dogs.



Purpose of the study:
The goal of the study was to determine the length of time that it took for
pills or capsules to enter the stomach after 1) dry pilling and 2) pilling
and then giving a 6 cc water chaser immediately following the administration
of the pill or capsule - referred to as a "wet swallow".



Study design:
30 cats were used. Fluoroscopy was used to evaluate the pill/capsule passage
at 30, 60, 90, 120, 180, 300 seconds.



Study results:
For the dry swallows:
No pills were in the stomach at 30 and 60 seconds. Only 6% of the pills were
in the stomach at 90 seconds. Only 13% of the pills were in the stomach at
120 seconds. And at 5 minutes only 36% of the pills were in the stomach.



For the wet swallows: (i.e., the pill was followed by 6 cc of water)
At 30 seconds, 90% of the pills were in the stomach. All pills were in the
stomach by 120 seconds.



The statistics were even worse for capsules when dry swallowed. By 5
minutes, only 16% of the capsules had made it to the stomach. 100% of
capsules followed by water chasers, were in the stomach by 60 seconds -
faster than for pills probably due to the smoother surface of a capsule
versus a pill.



Commentary:
"This is an interesting study that has considerable practical impact.
Although veterinarians have a huge arsenal of mediations and treatments
available to us, we still have a very poor understanding of some of the most
basic aspects of everyday practice. We routinely prescribe oral medications
in the form of tablets or capsules to cats.



It has been our assumption that when it was possible for the owner to
actually give the pills or capsule to the cat, it would make it into the
stomach reasonably rapidly. It turns out that this is inaccurate. After 5
minutes 84% of capsules and 64% of tablets are still sitting in the
esophagus. Similar results were published in another study by JP Graham
(American Journal of Veterinary Research 2000).



Practical outcome:
The main concern with this information is that if tablets and capsules sit
in the esophagus for a prolonged period of time, this can cause damage to
the tissues in this area. This damage can lead to esophagitis, which can
lead to nausea, vomiting and megaesophagus. At times, the esophagus can also
respond by developing an ulcer or stricture. The latter is a very serious
complication requiring aggressive therapy, preferably with balloon
dilatation.



In addition, we probably have all had that uncomfortable feeling when a
tablet we have taken has gotten stuck on the way down. This could be the
cause of vomiting in some cats that are medicated. It is quite frustrating
to win the battle to get the pill or capsule down a cat and then have it
vomited up several minutes later.



Both this abstract as well as the study published by Graham et al. clearly
point to the need to administer either water or food after a cat has been
pilled with a tablet or a capsule. This will hasten the movement into the
stomach and cut down on the chances of the tablet or capsule remaining in
the esophagus for a prolonged period of time. Although comparable studies
have not been done in dogs, this advice is sound in dogs, as well."
(End of quoted study)



.
 
__,_._,___ 
Susan J. DuBose  >^..^<
www.PetGirlsPetsitting.com
www.Tx.SiameseRescue.org
www.shadowcats.net
                                  "As Cleopatra lay in state,
                                   Faithful Bast at her side did wait,
                                   Purring welcomes of soft applause,
                                   Ever guarding with sharpened claws."
                                             Trajan Tennent



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