-----Original Message-----
>From: Lorrie <felineres...@frontier.com>
>Sent: Apr 27, 2013 1:00 PM
>To: felvtalk@felineleukemia.org
>Subject: Re: [Felvtalk] For Chang......Cat dying at home
>
>I also wonder why this indoor cat suddenly became FelV positive<<


            I've been wrestling with this. My + boy has been here since Jan of 
2012, and tested negative before I integrated him into one of my cat groups. 
After a very stressful bout with FLUTD and catherization, he just never 
recovered. Bloodwork eventually showed a very low WBC count, and a subsequent 
SNAP was positive for FeLV, neg for FIV. So, now I've exposed all those cats 
who live with him. I've been trying to figure it out, and here's one excerpt 
that helped my begin to understand.  I've also included the link to the whole 
article, but here is the relevant paragraph.

        " It’s the apparent incidence of regressive FeLV infection that will 
continue to challenge all of us…ie, what are the clinical consequences of 
latency in a SNAP negative, healthy cat. Based on information available today, 
the odds favor the cat…there is a good chance the cat will remain healthy, may 
eventually clear the proviral DNA, and they are NOT shedding FeLV as long as 
the virus remains as proviral DNA (latent). Some, however, don’t do as well…a 
small number of regressive infections will re-activate…this is the adult 
cat…with a history of having been healthy and FeLV negative for some time 
(years even). And despite the fact they may have never encountered another cat 
throughout life…they appear to develop disease spontaneously and may become 
progressive (IFA or SNAP positive, sick cat)…or…they may develop complications 
of their infection, including solid tumors (FeLV is an oncogenic 
retrovirus)…and may become IFA or SNAP negative!"

Here's a link to the complete article;

http://www.fvmace.org/FVMA_83rd_Annual_Conference/Proceedings/PDFS/2012%20FeLV%20&%20FIV.pdf

         It's really discouraged me. Makes me think it's probable that all  my 
"new" cats (those acquired since my move here in 2006) were once infected, and 
possibly latent. They've all come from this neighborhood. Right now I have one 
that has to become a housecat, but has been an outside cat all his 4 years. 
He's tested negative, and I've arranged for him to get the rFeLV vaccine, but 
is there any point? I just don't know.

         I'm very interewsted in what others think. This is all new to me. In 
30+ years of rescue, I've never had a cat test positive for FeLV.

Still trying  to get my head around this.

Margo

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