Hi all :)
Karen said
>We also have a very experienced rescue cat lady here
>who is giving interferon to negative cats for severe URI.
I remind to everybody that HUMAN Interferon can't be *injected*
in cats, but only given *orally*.
Feline Interferon (Virbagen Omega) can be given both injected and
orally, but this last way is a waste of money, because the effects
are exactly the same as with human Interferon.
I also point out that the first clinical trial, by Mahl and Maynard,
with injected Feline Interferon, was made on SYMPTOMATIC FeLV CATS,
the symptoms including also granulomatous stomatitis.
======================================================
SURVIVAL OF SYMPTOMATIC FELV OR FELV AND FIV POSITIVE CATS TREATED WITH
A RECOMBINANT FELINE OMEGA INTERFERON
M�hl P, Maynard L, Karine De Mari K, and Lebreux B
A study was designed to assess the efficacy of a recombinant feline
omega interferon (rFeIFNw) in the treatment of symptomatic FeLV or FeLV
and FIV positive cats. In a multicentric, controlled, randomised and
double blind clinical field trial, 48 FeLV or FeLV and FIV tested cats
were included with general clinical signs and/or chronic granulomatous
stomatitis. 28 cats were subcutaneously administered 1 million units
(MU) interferon per kg b.w. once a day for 5 days and 20 cats received a
placebo. Symptomatic treatment including antibiotherapy was allowed in
all cats. Cats were clinically observed for 6 months and death date was
recorded if applicable. Efficacy was assessed through the survival
probabilities which were calculated by the KAPLAN-MEIER method and
compared by the LOGRANK test. 13 (46%) cats died during the observation
period in rFeIFNw group and 15 (75%) in the placebo group. Comparison of
the survival curves showed a statistically significant difference
between groups (p = 0.0331). Safety of the product based on clinical
examination was excellent. After 5 SC injections of 1 MU/kg rFeIFNw, the
survival probability over a 6-month period of FeLV or FeLV and FIV
symptomatic cats was 2.2 times higher in the treated cats.
==============================================================
Moreover, in the NRA Gazette (the HTML page I sent) you read that
it is used in cats for calici: it's not FeLV, but it's in cats ;)
>These products are for use on dogs and cats.
>reduction of the duration and severity of fever and oral ulceration
>associated with feline calicivirus.
Take care
Paolo
