Dear Karolyn:

Does it really do any good (and no harm) to give vaccines to a cat whose 
immune system is compromised??  There is a lot of current info suggesting that it 
is not wise to give vaccines of any kind to a cat who is FeLV+.  Have any 
studies ever been done to demonstrate that vaccines do have a protective effect 
for immunosuppressed cats?  Multivalent vaccines are not recommended for even 
healthy cats, but I have not seen a vaccine for just Panleukopenia available in 
any of the vet supply cataloges or web sites.  That is the only virus the 
3-way is supposed to protect against that is truly life-threatening. 

My first FeLV+, Purrsia, came down with Panleukopenia at 10 wks. a few days 
after I rescued her, before she could be vaccinated for anything. At that time 
she tested negative for FeLV and FIV.  Since she had recovered from the P 
virus, there was no point in vaccinating her for that after the fact. But her 
playmate, Angel Eyes, was subsequently vaccinated with a 3-way before I found out 
she was FeLV+.  I will always wonder if that vaccine had a negative effect on 
her immune system.  Angel became symptomatic for FeLV and tested positive two 
weeks after Purrsia passed...for the next 8 months it seemed she might be one 
of the lucky ones who can live with the virus long-term, then the day after 
Xmas '03 she crashed and 14 days later was gone, just shy of 16 mos.

I agree that Panleukopenia is a nasty disease and so much more easily spread 
than FeLV or FIV.  Miraculously, I was able to successfully nurse my brave 
little Purrsia through it after the vet gave her virtually no chance to survive 
unless I hospitalized her, but I could not afford to do that.  I think the fact 
I had started her immediately on Animal Stress Pack with Transfer Factors 
(from 4Life Products and available from KV Vet Supply) at the first sign of a 
temp helped to stem the tide as the characteristic horrendous diarrhea never 
digressed to being hemmoraghic in her case.  The key seems to be keeping more 
fluids and nutrition going in than is coming out and it took round the clock 
syringe feeding, subQ fluids and meds to ward off opportunistic infections.  It can 
take small kittens out in a matter of hours and is an agonizing way for a cat 
to die.

Since Panleukopenia is a corona virus (related to the canine parvovirus), the 
factor of viral load comes into play and so multi-cat households or catteries 
are more at risk of being infected.  And that would also apply to feral 
colonies where they may be many unvaccinated cats.  Kittens and very old cats are 
most at risk, of course.  

I currently have three FeLV+ cats among 19.  Two of them are just over a year 
old and had been doing fine until just recently...both are now developing the 
tell-tale gingivitis.  Neither of them has had any vaccines.  The third 
kitten tested positive at 6 weeks...he is just 12 weeks now and needs to be 
retested.  He has not been vaccinated, either.  I do keep the positives separated 
from the rest of my cats, and leave my rubber boots that I wear to the horse 
stable outside.  When I go out wearing shoes, I spray the soles with bleach spray 
when I get back and do not usually wear shoes in the house.  I do worry, and 
wonder which represents a greater risk, vaccines for a positive cat, or the 
chance I will bring something pathogenic home.

Sally in San Jose 

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