Dear FIS colleagues,

Thanks to Karl and Joe for their responses. Sorry that I cannot answer 
them, but herein is the draft we are currently working in. We continue 
looking for partners (the easiest if they belong to the European Union). 
Comments are welcome...

best wishes

Pedro
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 *
*

*TOWARDS A NEURODYNAMIC CENTRAL THEORY--REVISITING CAJAL'S "LAW OF 
MAXIMUM ECONOMY"*

 

Arguably, one of the most dramatic absences in the contemporary 
scientific system occurs in the neurosciences. The ongoing 
neurocomputational, neuromolecular, neuroinformatic and neuroimaging 
revolutions (to name but a few of the emerging disciplines responsible 
of the enormous experimental data-accumulation taking place in 
neurosciences) have not been accompanied by a parsimonious theoretical 
synthesis yet. Thereupon, the lack of a central neurodynamic theory 
playing a "circulating role" between all the neural fields, similar to 
the Darwinian theory's central role in the biological realm (or 
classical mechanics in physics), is creating an intellectual vacuum that 
negatively influences on the neurosciences themselves, humanities and 
the social sciences.

The theoretic development herein envisioned will be grounded, 
historically, in Cajal's  law of "maximum economy in space, time, and 
interconnecting matter" (Textura, pp. 95-106), which will be revisited 
from different perspectives. On the one side, both M. Leyton (1992, 
2001) and K.P. Collins & P.C. Marijuán (1997) have proposed overarching 
optimization principles related to symmetry-operations in the neural 
maps that somehow imply minimization of excitations (echoing ideas 
already discussed by Freud himself, and more recently by Barlow, 
Rossler, Edelman, and Arbib; see also Cherniak, Griffin, Chen, etc. 
about structural optimization). Then, the emergence of the Action / 
Perception cycle as a basic building block to organize adaptive behavior 
would be inscribed within the "closure" operations of the ongoing 
neurocomputational minimization processes performed upon the excitation 
/inhibition collective variable, topologically distributed, defined both 
globally and locally as a sort of "entropy" in the neuronal mappings and 
rhythms (Gibson, Turvey, Kelso, Buzsáki). Further, the integration of 
such basic minimization processes within the main brain architectures 
--cerebellar, thalamocortical, limbic, frontal-- has to be achieved in a 
way that simultaneously produces the outcomes of adaptive behavior, 
meaning, memory contents, and the possibility of frontal "conceptual" 
guidance. Recent works of authors such as Rodolfo Llinás, Alain Berthoz, 
Jeff Hawkins, Tomás Ortiz, and Joaquín Fuster (e.g., the "cognits" 
proposal) would imply advancements in those particular areas for the 
proposed scheme.

Indeed, the quest for a neurodynamic optimization principle in the 
neurosciences, and the central theory to be elaborated upon, that we 
must credit to Cajal's insights one hundred years ago, appears as a 
long-term interdisciplinary enterprise. If finally successful, it would 
boost our present understanding of information processes in the Central 
Nervous System and in a plethora of related disciplines, from 
neuro-robotics to social fields...

Note: FISers Michael Leyton, Andrei Khrennikov, Fivos Panetsos, Rafa 
Lahoz, and Pedro Marijuan are already involved in this tentative 
project, Tomás Ortiz and Joaquin Fuster, quite probably, can be enlisted 
too.

-- 

-------------------------------------------------
Pedro C. Marijuán
Grupo de Bioinformación / Bioinformation Group
Instituto Aragonés de Ciencias de la Salud
Avda. Gómez Laguna, 25, Pl. 11ª
50009 Zaragoza. España / Spain
Telf: 34 976 71 3526 (& 6818) Fax: 34 976 71 5554
pcmarijuan.i...@aragon.es
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